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On the Optimization of the Microstructural and Mechanical Properties of Model Ni-Based Superalloys Through the Alloying Effects of Refractory Mo and W Elements Eriş, Rasim; Akdeniz, Mahmut Vedat; Mehrabov, Amdulla (2022-05-01) In the design and development of next-generation Ni-based superalloys, the addition of refractory impurity elements not only induces better degree of bonding strengthening, but also helps in maintaining structural stabilit...
Beam dynamic studies at accelerator system of gun for a self-amplified spontaneous emission free electron laser project Yildiz, H. Duran; Porsuk, D.; Yıldız, İlker; Cakir, R. (2022-01-01) One of the important factors in high radiation generation facilities is the production of a high quality electron beam. To do that, the requirements of an optical electron source, such as current, radiation emission, etc. ...
Preclinical toxicity test results of a new antiviral–immune-modulator compound consisting of flavonoid molecules (COVID-19 clinical trial preliminary data) Budak, Gürer; ÖZKAN, SEÇİL; BUDAK, Mehmet; Şeker, Tamay; MERYEMOĞLU, BAHAR; Miran, Şükran Selin; Çoban, Canan Çakır; Tarkun, Örkun (2022-01-01) Aim: Isolated specific glycone–aglycone conjugated flavonoids which are investigated for their effect of bioavailability and molecular concentrations. The specific formula is then tested via in vitro and in vivo cytotoxici...
Critical analysis of zeolite 4A synthesis through one-pot fusion hydrothermal treatment approach for class F fly ash Akın, Süleyman Şener; Kirdeciler, Salih Kaan; Kazanç Özerinç, Feyza; Akata Kurç, Burcu (2021-10-01) In this study, ‘‘One-pot fusion assisted hydrothermal synthesis’’ approach was employed to understand the nucleation and crystallization behaviour of the fusion product of Class F fly ash for zeolite 4A synthesis. Two sets...
Enhancing esophageal repair with bioactive bilayer mesh containing FGF Cesur, Ozkan; Endoğan Tanır, Tuğba; Celepli, Pinar; Ozarslan, Fatma; Hucumenoglu, Sema; KARAİBRAHİMOĞLU, Adnan; Hasırcı, Nesrin (2021-09-01) We aimed to prepare a bioactive and biodegradable bilayer mesh formed by fibroblast growth factor (FGF) loaded gelatin film layer, and poly epsilon-caprolactone (PCL) film layer, and to investigate its treatment efficacy o...
Design, synthesis, molecular docking and ADME studies of novel indole-thiazolidinedione derivatives and their antineoplastic activity as CDK6 inhibitors Kışla, Mehmet Murat; Zengin Karadayı, Fikriye; Baran, Sercan; Doğan, Tuğba; Mutlu, Pelin; Ateş-Alagöz, Zeynep (2021-09-01) Several 5-((5-substituted-1H-indole-3-yl)methylene)-3-(2-oxo-2-(3/4-substituted-phenylethyl)-thiazolidine-2,4-dione derivatives (9–24) were designed and synthesized as CDK6 inhibitors, and their anticancer activity w...
Design, synthesis, molecular docking and ADME studies of novel indole-thiazolidinedione derivatives and their antineoplastic activity as CDK6 inhibitors Kışla, Mehmet Murat; Zengin Karadayı, Fikriye; Baran, Sercan; Doğan, Tuğba; Mutlu, Pelin; Ateş-Alagöz, Zeynep (2021-09-01) Several 5-((5-substituted-1H-indole-3-yl)methylene)-3-(2-oxo-2-(3/4-substituted-phenylethyl)-thiazolidine-2,4-dione derivatives (9–24) were designed and synthesized as CDK6 inhibitors, and their anticancer activity w...
Microporous vanadosilicate films with tailorable V4+/V5+ ratio to achieve enhanced visible-light photocatalysis Kuzyaka, Duygu; Uzun, Ceren; Yıldız, İlker; Kaya, Murat; Akata Kurç, Burcu (2021-08-01) This study investigates the changes induced into the photocatalytic activity under solar light irradiation upon changing the structural film properties and tailor the concentration of defects in microporous vanadosilicate ...
The Site Preferences of Transition Elements and Their Synergistic Effects on the Bonding Strengthening and Structural Stability of gamma '-Ni3Al Precipitates in Ni-Based Superalloys: A First-Principles Investigation Eriş, Rasim; Akdeniz, Mahmut Vedat; Mehrabov, Amdulla (2021-04-01) Advanced mechanical properties of Ni-based superalloys strongly depend on the site preferences of alloying X elements in gamma '-Ni3Al-X precipitates, which are associated with the partial bonding characteristics between N...
Evaluation of methylation profiles of an epidermal growth factor receptor gene in a head and neck squamous cell carcinoma patient group Mutlu, M.; Mutlu, Pelin; Azarkan, S.; Baylr, Ö.; Öcal, B.; Saylam, G.; KORKMAZ, MEHMET HAKAN (2021-03-23) Upregulation of the epidermal growth factor receptor (EGFR) gene has shown an important impact on the development of head and neck cancers due to its important regulation role on multiple cell signaling pathways. The aim o...
Improvement of electrical characteristics of SnSe/Si heterostructure by integration of Si nanowires Coskun, E.; Güllü, Hasan Hüseyin; Emir, C.; Parlak, M. (2021-03-01) In this study, the effects of the nanowire geometry on Si wafer substrate were investigated for the SnSe/Si-nanowire heterojunction device and the obtained results were compared with the one fabricated on planar Si surface...
Development of three-enzyme lactose amperometric biosensor modified by nanosized poly (meta-phenylenediamine) film Pyeshkova, V.M.; Dudchenko, O.Y.; Soldatkin, O.O.; Alekseev, S.A.; Şeker, Tamay; Kurc, B. Akata; Dzyadevych, S.V. (2021-01-01) New three-enzyme lactose amperometric biosensor based on platinum disc electrode modified by nanosized semipermeable poly (meta-phenylenediamine) film was developed in this work. It was studied the influence of different c...
Ultrasonication for Environmentally Friendly Preparation of Antimicrobial and Catalytically Active Nanocomposites of Cellulosic Textiles Kwiczak-Yigitbasi, Joanna; Demir, Mine; Ahan, Recep Erdem; Canlı, Sedat; ŞEKER, URARTU ÖZGÜR ŞAFAK; BAYTEKİN, BİLGE (2020-12-01) The global demand for sustainable and functional fibers and textile materials is increasing with the pressure to limit the synthetic petroleum-based counterparts. In this study, we use ultrasonication for the preparation o...
Granitik Buzul Çakıllarında Zirkon Tipolojisi Çalışması: Toridler’den Örnek Bir Çalışma (Türkiye) Köksal, Serhat (2020-11-01) Gondwana’nın kuzey kenarına ait Geç Ordovisiyen buzul kayaçlarına, Torid’lerde ve Güneydoğu Anadolu Otokton Kuşağı’nda rastlanmaktadır. Bu çalışmada; Doğu Toridler’de Feke-Saimbeyli-Ceralan (Adana) (DPK-30), Feke-Gökmenler...
Optical and Nanomechanical Properties of Ga(2)Se(3)Single Crystals and Thin Films IŞIK, MEHMET; Emir, Cansu; Güllü, Hasan Hüseyin; Hasanlı, Nızamı (Springer Science and Business Media LLC, 2020-10-01) The optical and nanomechanical properties of Ga(2)Se(3)single crystals and thin films were investigated using reflection, transmission, and nanoindentation measurements. The reflection spectrum recorded in the 525- to 1100...
First-principles studies of Tin+1SiN(n) (n=1, 2, 3) MAX phase Surucu, Gokhan; Güllü, Hasan Hüseyin; CANDAN, ABDULLAH; YILDIZ, BUĞRA; Erkisi, Aytac (Informa UK Limited, 2020-09-01) In this study, the structural, electronic, mechanical, lattice dynamical and thermodynamic characteristics of ( 1, 2 and 3) phase compounds were investigated using the first principle calculations. These ternary nitride co...
Real-time gas monitoring at the Tekke Hamam geothermal field (Western Anatolia, Turkey): an assessment in relation to local seismicity Süer, Selin; Güleç, Nilgün Türkan; Parlaktuna, Mahmut (Springer Science and Business Media LLC, 2020-08-01) This study presents the results of a real-time gas monitoring experiment conducted, via the use of a quadrupole mass spectrometer, in a mofette field within the Tekke Hamam geothermal site in western Anatolia (Turkey), a t...
Material and Si-based diode analyses of sputtered ZnTe thin films Güllü, Hasan Hüseyin; Surucu, O. Bayrakli; Isik, M.; Terlemezoglu, M.; Parlak, M. (Springer Science and Business Media LLC, 2020-07-01) Structural, optical, and electrical properties ZnTe thin films grown by magnetron sputtering technique were studied by X-ray diffraction, atomic force microscopy, Raman spectroscopy, and electrical conductivity measurement...
Investigation of structural, electronic, magnetic and lattice dynamical properties for XCoBi (X: Ti, Zr, Hf) Half-Heusler compounds Surucu, Gokhan; IŞIK, MEHMET; CANDAN, ABDULLAH; Wang, Xiaotian; Güllü, Hasan Hüseyin (Elsevier BV, 2020-06-15) Structural, electronic, magnetic, mechanical and lattice dynamical properties of XCoBi (X: Ti, Zr, Hf) Half-Heusler compounds have been investigated according to density functional theory and generalized gradient approxima...
Doxorubicin-loaded magnetic nanoparticles downregulate expression of anti-apoptotic genes in resistant breast cancer cells. Yalçın Azarkan, Serap; Mutlu, Pelin; Ünsoy, Gözde; Khodadust, Rouhollah; Gündüz, Ufuk (2020-06-01)

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