Flow-induced vibration analysis of constricted artery models with surrounding soft tissue

Salman, Huseyin Enes
Yazıcıoğlu, Yiğit
Arterial stenosis is a vascular pathology which leads to serious cardiovascular diseases. Blood flow through a constriction generates sound and vibration due to fluctuating turbulent pressures. Generated vibro-acoustic waves propagate through surrounding soft tissues and reach the skin surface and may provide valuable insight for noninvasive diagnostic purposes. Motivated by the aforementioned phenomena, vibration of constricted arteries is investigated employing computational models. The flow-induced pressure field in an artery is modeled as broadband harmonic pressure loading based on previous studies in the literature and applied on the inner artery wall. Harmonic analysis is performed for determining radial velocity responses on the outer surface of the models. Results indicate that stenosis severities higher than 70% lead to significant increase in response amplitudes, especially at high frequencies between 250 and 600Hz. The findings agree well with experimental and theoretical results in the literature considering bending mode frequencies, amplitude scales, and mainly excited frequency ranges. It is seen that artery vibration is sensitive to the phase behavior of pressure loading but its effect becomes less significant with the presence of surrounding tissue. As the surrounding tissue thickness increases, radial velocity response amplitudes decrease but the effect of changes in tissue elastic modulus is more pronounced. (C) 2017 Acoustical Society of America.


Evaulation of spatial and spatio-temporal regularization approaches in inverse problem of electrocardiography
Önal, Murat; Serinağaoğlu Doğrusöz, Yeşim; Department of Electrical and Electronics Engineering (2008)
Conventional electrocardiography (ECG) is an essential tool for investigating cardiac disorders such as arrhythmias or myocardial infarction. It consists of interpretation of potentials recorded at the body surface that occur due to the electrical activity of the heart. However, electrical signals originated at the heart suffer from attenuation and smoothing within the thorax, therefore ECG signal measured on the body surface lacks some important details. The goal of forward and inverse ECG problems is to r...
Non-invasive acoustic detection of vascular diseases from skin surface using computational techniques with fluid-structure interaction
Salman, Hüseyin Enes; Yazıcıoğlu, Yiğit; Ciğeroğlu, Ender; Department of Mechanical Engineering (2018)
Atherosclerosis is a cardiovascular disease in which arterial occlusion adversely affects blood circulation. Because of the narrowing of the artery, the blood flow is disturbed and a recirculating flow occurs at the downstream of the stenosis exit. The dynamic pressure fluctuations on the inner arterial wall cause the blood vessel wall to vibrate and the resulting acoustic energy propagates through the surrounding soft tissue and reaches the skin surface. To understand the problem in more detail, computatio...
Prognostic Factors for Amputation Following Surgical Repair of Lower Extremity Vascular Trauma: A Systematic Review and Meta-Analysis of Observational Studies
Perkins, Zane B.; Yet, Barbaros; Glasgow, Simon; Marsh, William; Brohi, Karim; Rasmussen, Todd E.; Tai, Nigel R. (2014-06-01)
Background: Lower extremity vascular trauma (LEVT) is a major cause of amputation. A clear understanding of prognostic factors for amputation is important to inform surgical decision-making, patient counselling and risk stratification. The aim was to develop an understanding of prognostic factors for amputation following surgical repair of LEVT. Methods: A systematic review was conducted to identify potential prognostic factors. Bayesian meta-analysis was used to calculate an absolute (pooled proportion) a...
Investigation of on skin surface response due to acoustic radiation from stenosed blood vessels
Salman, Huseyin E.; Yazıcıoğlu, Yiğit (2015-11-02)
Arterial stenosis is a form of cardiovascular disease which leads to highest rate of fatalities worldwide. When stenosis is present in coronary arteries, it leads to heart attack and often sudden death. Arterial disease is usually not confined to critical organs such as the heart and the brain but observed throughout the peripheral cardiovascular system. When an artery has a diameter reduction, acoustic radiation originating from this constriction propagates through soft tissues and reaches to skin surface....
Cancer modeling via biologically validated genes
Karakelle, Barış Su; Purutçuoğlu Gazi, Vilda; Ürün, Yüksel (2017-05-10)
The cancer disease is the second most common disease type seen after the frequency of the cardiovascular diseases. The frequency of this genetic disease changes with respect to the gender. Accordingly, the gynecological cancer, which covers ovarian, endometrial or cervical cancer, is the second most common cancer type in women after the breast cancer. Similar to other cancer types, the gynecological cancer is the system disease, meaning that the malfunctions and mutations in the gene regulatory ...
Citation Formats
H. E. Salman and Y. Yazıcıoğlu, “Flow-induced vibration analysis of constricted artery models with surrounding soft tissue,” JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, pp. 1913–1925, 2017, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/42613.