Computational study of scattering from healthy and diseased red blood cells

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2010-07-01

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Ergül, Özgür Salih
Gurel, Levent

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We present a comparative study of scattering from healthy red blood cells (RBCs) and diseased RBCs with deformed shapes. Scattering problems involving three-dimensional RBCs are formulated accurately with the electric and magnetic current combined- field integral equation and solved efficiently by the multilevel fast multipole algorithm. We compare scattering cross section values obtained for different RBC shapes and different orientations. In this way, we determine strict guidelines to distinguish deformed RBCs from healthy RBCs and to diagnose various diseases using scattering cross section values. The results may be useful for designing new and improved flow cytometry procedures. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3467493]

Subject Keywords

Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Biomaterials, Biomedical Engineering

URI

https://hdl.handle.net/11511/44058

Journal

JOURNAL OF BIOMEDICAL OPTICS

DOI

https://doi.org/10.1117/1.3467493

Collections

Department of Electrical and Electronics Engineering, Article

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Citation Formats

Ö. S. Ergül and L. Gurel, “Computational study of scattering from healthy and diseased red blood cells,” JOURNAL OF BIOMEDICAL OPTICS, pp. 0–0, 2010, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/44058.