Synthesis of 3-azabicyclo[3.3.0]octane framework and a novel tricyclicaminoether

Date

2003-01-01

Author

Kaniskan, HU
Doğan, Özdemir

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The efficient synthesis of 3-azabicyclo[3.3.0]octane derivative 1 and a novel tricyclicaminoether 11 has been achieved in seven steps using commercially available starting materials and commonly used reagents. The key steps are the intramolecular ring opening of epoxide 7 providing tricyclic aminoalcohol 3 and Baeyer-Villiger oxidation of ketone 8 providing the corresponding lactone 2. Both reactions proceeded regiospecifically.

Subject Keywords

Organic Chemistry

URI

https://hdl.handle.net/11511/44793

Journal

SYNTHETIC COMMUNICATIONS

DOI

https://doi.org/10.1081/scc-120025195

Collections

Department of Chemistry, Article

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Citation Formats

H. Kaniskan and Ö. Doğan, “Synthesis of 3-azabicyclo[3.3.0]octane framework and a novel tricyclicaminoether,” SYNTHETIC COMMUNICATIONS, pp. 3833–3841, 2003, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/44793.