One-pot synthesis of N-substituted 2-methyl-4,5,6,7-tetrahydroindole derivatives

Date

2004-12-20

Author

Tanyeli, Cihangir
Yazicioglu, EY

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We describe the preliminary results of one-pot syntheses of various N-substituted 2-methyl-4,5,6,7-tetrahydroindole derivatives from 2-(2-bromoailyl)cyclohexanone and the corresponding primary amines in good yields. Aliphatic amines were directly converted to tetrahydroindoles, whereas aromatic amines needed an extra base treatment step to complete the transformation.

Subject Keywords

Organic Chemistry, Biochemistry, Drug Discovery

URI

https://hdl.handle.net/11511/45677

Journal

TETRAHEDRON LETTERS

DOI

https://doi.org/10.1016/j.tetlet.2004.10.145

Collections

Department of Chemistry, Article

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Citation Formats

C. Tanyeli and E. Yazicioglu, “One-pot synthesis of N-substituted 2-methyl-4,5,6,7-tetrahydroindole derivatives,” TETRAHEDRON LETTERS, pp. 9627–9629, 2004, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/45677.