A novel one-pot, three-component reaction for the synthesis of isocoumarin-condensed pyrazoles

Date

2011-03-30

Author

OZCAN, Sevil
Dengiz, Çağatay
DELIOMEROGLU, Murat K.
ŞAHİN, Ertan
BALCI, METİN

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The one-pot, three-component reaction of substituted homophthalic anhydrides with hydrazine in DMF as solvent and reactant, at reflux temperature, afforded isochromeno[3,4-c]pyrazole-5(2H)-one derivatives in high yields. The mechanism and roles of the substrates were investigated and it was found that cyclic hydrazides were formed as intermediates.

Subject Keywords

Organic Chemistry, Biochemistry, Drug Discovery

URI

https://hdl.handle.net/11511/36317

Journal

TETRAHEDRON LETTERS

DOI

https://doi.org/10.1016/j.tetlet.2011.01.114

Collections

Department of Chemistry, Article

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Citation Formats

S. OZCAN, Ç. Dengiz, M. K. DELIOMEROGLU, E. ŞAHİN, and M. BALCI, “A novel one-pot, three-component reaction for the synthesis of isocoumarin-condensed pyrazoles,” TETRAHEDRON LETTERS, pp. 1495–1497, 2011, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/36317.