Paper Based Glucose Biosensor Using Graphene Modified with a Conducting Polymer and Gold Nanoparticles

2017-01-01
GOKOGLAN, Tugba Ceren
KESİK, Melis
SOYLEMEZ, Saniye
YÜKSEL, Recep
Ünalan, Hüsnü Emrah
Toppare, Levent Kamil
Show full item record
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
206
views
0
downloads
In this work a novel approach was reported for glucose detection using disposable paper based electrodes consisting graphene modified with a conducting polymer, glucose oxidase (GOx) and gold nanoparticles. For the first time, a conducting polymer; poly(9,9-di-(2-ethylhexyl)-fluorenyl-2,7-diyl)-end capped with 2,5-diphenyl-1,2,4-oxadiazole (PFLO) was spread over graphene coated papers and used as a matrix for glucose detection. To finalize the desired biosensor, the enzyme GOx was immobilized with gold nanoparticles (AuNPs) via physical adsorption technique. Oxygen consumption was followed at -0.7 V vs Ag wire in a 50 mM, pH 6.0 phosphate buffer. The amperometric response of the GOx/graphene/PFLO/AuNPs-modified electrode was found to be linearly proportional to the glucose concentration. The fabricated biosensor revealed a high sensitivity for glucose in a linear range from 0.1 to 1.5 mM with a low detection limit of 0.081 mM at a signal-to-noise ratio of 3. K-M(App), I-max, and sensitivity were calculated as 0.229 mM, 2.198 mu A, and 7.357 mu A/mM cm(2), respectively. Finally, the constructed disposable biosensor was successfully utilized for the determination of glucose in commercial beverages. (C) 2017 The Electrochemical Society. All rights reserved.
Renewable Energy, Sustainability and the Environment, Electrochemistry, Materials Chemistry, Electronic, Optical and Magnetic Materials, Surfaces, Coatings and Films, Condensed Matter Physics
https://hdl.handle.net/11511/47114
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
Department of Metallurgical and Materials Engineering, Article

Suggestions

PARTIAL MOLAR PROPERTIES OF MGCL2 IN MGCL2-KCL-CACL2 MELTS
ZHU, J; Karakaya, İshak; THOMPSON, WT (The Electrochemical Society, 1988-01-01)
To further the understanding of electrolytes of value in industrial magnesium electrolysis, the reversible emf for the formation of in fused salts containing and was studied. The data made possible the calculation of thermodynamic solution properties which were used with other data to construct features of the ternary phase diagram. The multiple discrete complex anion (MDCA) model was tested against the thermodynamic findings from the present study. Reasonable agreement was obtained between the experimen...
Silver Nanoparticles Added Polymer Film Prepared by Electrochemical Route for Surface Enhanced Raman Scattering Applications
Khadim, Raisan; Uzun, Ceren; Cihaner, Atilla; Kaya, Murat (The Electrochemical Society, 2019-03-02)
A simplemethod for the fabrication of stable and highly active surface enhanced Raman scattering (SERS) substrate by exploiting the optical properties of the silver nanoparticles (AgNPs) and organizational characteristics of the polymer is presented. Homogeneous distribution ofAgNPs is achieved with the usage of poly (4,7-di-2,3-dihydrothieno [3,4-b] [1,4] dioxin-5-yl-2,1,3 benzoselena diazole) (PESeE) film coated on the indium tin oxide glass (ITO) surface. The obtained structure ensured the emergence of a...
Microfluidic and Fuel Adulteration Sensing by Using Chiral Metamaterial Sensor
BAKIR, MEHMET; KARAASLAN, MUHARREM; Unal, Emin; Karadag, Faruk; Alkurt, Fatih Ozkan; ALTINTAŞ, OLCAY; Dalgac, Sekip; Sabah, Cumali (The Electrochemical Society, 2018-08-08)
In this study, Chiral Metamaterial Sensor (CMS), which is designed by utilizing a Split Ring Resonators (SRR) has been employed to reveal the two different types of sensor applications by experimentally and numerically. These applications include purity demonstration of methanol, ethanol and isopropyl alcohol (IPA) and fuel adulteration applications for petrol. All of the validations have been realized by measuring the complex permittivity values and reflection coefficients by using a vector network analyze...
Application of an Efficient Amperometric Glucose Sensing Electrode Based on a Bilayer Polymer Film Platform
Kaya, Hava Zekiye; Söylemez, Saniye; Udum, Yasemin Arslan; Toppare, Levent Kamil (The Electrochemical Society, 2018-12-27)
A new approach was developed using a combination of a conducting polymer; poly(3,4-ethylenedioxythiophene) (PEDOT) with the electrochemically produced polymer of N-ferrocenyl-3-(1H-pyrrol-1-yl) aniline, (PFcPyBz) layer for the enzyme scaffolding resulting in excellent analytical parameters. To organize such a surface, graphite electrode was coated with a PEDOT layer and it was used as a transducer for electrochemical deposition of the polymer of a newly synthesized FcPyBz monomer. Using a PEDOT layer as the...
Syntheses and Electrochemical Characterization of Low Oxidation Potential Nitrogen Analogs of Pedot as Electrochromic Materials
Hacioglu, Serife O.; Yigit, Deniz; Ermis, Emel; Soylemez, Saniye; GÜLLÜ, Mustafa; Toppare, Levent Kamil (The Electrochemical Society, 2016-01-01)
In this study, the electropolymerization of ethyl andmethyl substituted asymmetrical nitrogen analogs of 3,4-ethylenedioxythiophene (OEt and OMe) were synthesized, characterized and their electrochemical properties were investigated. Both polymers (POEt and POMe) were synthesized electrochemically and characterized using spectroelectrochemical technique to determine optical changes of the resulting polymer films. Electrochemical studies demonstrated that these polymers exhibited a significantly low oxidatio...
Citation Formats
T. C. GOKOGLAN, M. KESİK, S. SOYLEMEZ, R. YÜKSEL, H. E. Ünalan, and L. K. Toppare, “Paper Based Glucose Biosensor Using Graphene Modified with a Conducting Polymer and Gold Nanoparticles,” JOURNAL OF THE ELECTROCHEMICAL SOCIETY, pp. 0–0, 2017, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/47114.
METU IIS - Integrated Information Service open@metu.edu.tr