Computerized hybrid decision-making system for hormone replacement therapy in menopausal women

Bacak, Hikmet Özge
Leblebicioğlu, Mehmet Kemal
BACKGROUND: The diversity of the results of different hormone replacement therapy (HRT) protocols and the fuzziness of the conclusions have caused problems in routine clinical practice.


In vitro and in vivo evaluation of the effects of demineralized bone matrix or calcium sulfate addition to polycaprolactone-bioglass composites
ERDEMLİ, ÖZGE; Captug, O.; Bilgili, H.; ORHAN, DİCLEHAN; Tezcaner, Ayşen; Keskin, Dilek (Springer Science and Business Media LLC, 2010-01-01)
The objective of this study was to improve the efficacy of polycaprolactone/bioglass (PCL/BG) bone substitute using demineralized bone matrix (DBM) or calcium sulfate (CS) as a third component. Composite discs involving either DBM or CS were prepared by compression moulding. Bioactivity of discs was evaluated by energy dispersive X-ray spectroscopy (ESCA) and scanning electron microscopy (SEM) following simulated body fluid incubation. The closest Calcium/Phosphate ratio to that of hydroxyl carbonate apatit...
Recognizing Obesity and Comorbidities in Sparse Data
Uzuner, Oezlem (Oxford University Press (OUP), 2009-07-01)
In order to survey, facilitate, and evaluate studies of medical language processing on clinical narratives, i2b2 (Informatics for Integrating Biology to the Bedside) organized its second challenge and workshop. This challenge focused on automatically extracting information on obesity and fifteen of its most common comorbidities from patient discharge summaries. For each patient, obesity and any of the comorbidities could be Present, Absent, or Questionable (i.e., possible) in the patient, or Unmentioned in ...
Feedback controlled electrical nerve stimulation: A computer simulation
Doruk, R. Ozgur (Elsevier BV, 2010-07-01)
The role of repetitive firing in neurophysiologic or neuropsychiatric disorders, such as Parkinson, epilepsy and bipolar type disorders, has always been a topic of medical research as therapies target either the cease of firing or a decrease in its frequency. In electrotherapy, one of the mechanisms to achieve the purpose in point is to apply a low density electric current to the nervous system. In this study, a computer simulation is provided of a treatment in which the stimulation current is computed by n...
Improving the sub-cortical gm segmentation using evolutionary hierarchical region merging
Çiftçioğlu, Mustafa Ulaş; Gökçay, Didem; Department of Medical Informatics (2011)
Segmentation of sub-cortical Gray Matter (GM) structures in magnetic resonance brain images is crucial in clinic and research for many purposes such as early diagnosis of neurological diseases, guidance of surgical operations and longitudinal volumetric studies. Unfortunately, the algorithms that segment the brain into 3 tissues usually suffer from poor performance in the sub-cortical region. In order to increase the detection of sub-cortical GM structures, an evolutionary hierarchical region merging approa...
Decision support system for Warfarin therapy management using Bayesian networks
Yet, Barbaros; Raharjo, Hendry; Lifvergren, Svante; Marsh, William; Bergman, Bo (2013-05-01)
Warfarin therapy is known as a complex process because of the variation in the patients' response. Failure to deal with such variation may lead to death as a result of thrombosis or bleeding. The possible sources of variation such as concomitant illnesses and drug interactions have to be investigated by the clinician in order to deal with the variation. This paper describes a decision support system (DSS) using Bayesian networks for assisting clinicians to make better decisions in Warfarin therapy managemen...
Citation Formats
H. Ö. Bacak, M. K. Leblebicioğlu, A. TANAÇAN, and M. S. BEKSAÇ, “Computerized hybrid decision-making system for hormone replacement therapy in menopausal women,” TECHNOLOGY AND HEALTH CARE, pp. 49–59, 2019, Accessed: 00, 2020. [Online]. Available: