Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency

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Date

2018-07-01

Author

Gul, Ersin
Sayar, Esra Hazar
Gungor, Bilgi
Eroglu, Fehime Kara
Surucu, Naz
Keleş, Sevgi
Güner, Şükrü Nail
Findik, Siddika
Alpdundar, Esin
Ayanoğlu, İhsan Cihan
Kayaoğlu, Başak
Geckin, Busra Nur
Sanli, Hatice Asena
Kahraman, Tamer
Yakicier, Cengiz
Müftüoğlu, Meltem
Oğuz, Berna
Çağdaş Ayvaz, Deniz Nazire
Gürsel, İhsan
Özen, Seza
Reisli, İsmail
Gürsel, Mayda

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Background: Pathological inflammatory syndromes of unknown etiology are commonly observed in ataxia telangiectasia (AT) and Artemis deficiency. Similar inflammatory manifestations also exist in patients with STING-associated vasculopathy in infancy (SAVI).

Subject Keywords

Primary immunodeficiencies, Autoinflammation, Ataxia telangiectasia, Artemis deficiency, Type I IFN, Interferonopathy, Neutrophil extracellular traps, NETosis

URI

https://hdl.handle.net/11511/49270

Journal

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

DOI

https://doi.org/10.1016/j.jaci.2017.10.030

Collections

Department of Biology, Article

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Citation Formats

E. Gul et al., “Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency,” JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, pp. 246–257, 2018, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/49270.