Metabolik+genetik+biyokimyasal reaksiyon mühendisliği prensipleriyle rekombinant enzim üretimi


Metabolizma Penceresinden Genetiği Değiştirilmiş Gıdalar
Gültekin, Güzin Candan (null; 2015-04-18)
Study of bone characteristics and muscle quality in metabolic disorders
Bozkurt, Özlem; Severcan, Feride; Department of Biology (2012)
Although the effects of diabetes on bone mineral content has been studied, little is known about the structural alterations in collagen, maturation of apatite crystals and carbonate content in diabetic bone. The first part of this study aimed to investigate the mineral and organic properties of cortical, trabecular and growth plate regions of rat femur tissues in type I diabetes using FTIR microspectroscopy and Vickers microhardness test. A decrease in mineral content (degree of mineralization), decrease in...
Characterization and promoter identification of metastasis associated protein 1 in human colorectal carcinoma cell lines
Tunçay Çağatay, Seda; Erson Bensan, Ayşe Elif; Department of Biology (2014)
Metastasis associated protein 1 (MTA1) is a member of the nuclear remodeling and histone deacetylase (NuRD) complex, which is known to repress the expression of several tumor suppressor genes and has been widely linked to tumor metastasis. 15-lipoxygenase-1 (15-LOX-1) is a lipid metabolizing enzyme that has tumor suppressive properties and is silenced by the NuRD complex in colorectal cancer (CRC). We have previously shown that reexpression of 15-LOX-1 inhibited metastasis in CRC, inhibited the inflammatory...
Metanol Dehidrasyonu İle Dimetil Eter (dme) Sentezi
Doğu, Timur(2008-12-31)
Metanol dehidrasyonu ile dimetileter sentezi yakıt teknolojileri açısından önem taşımaktadır. Asit karakterli katalizörler üzerinde metanol dehidrasyon çalışmaları yürütülecektir.
Human growth hormone production by metabolically engineered b. subtilis : feeding strategy development
Gökbudak, Burcu; Çalık, Pınar; Özdamar, Tunçer H.; Department of Chemical Engineering (2013)
In this study, the aim is to develop an effective feeding strategy for therapeutically important protein, recombinant human growth hormone (rhGH) production by Bacillus subtilis scoC knockout (scoC-) strain carrying pMK4::pre(subC)::hGH plasmid. In the first part of the research program, laboratory scale air filtered shake bioreactor experiments were conducted to optimize the production conditions. Thereafter, semi-batch production processes at pilot scale bioreactor system were performed by designing expon...
Citation Formats
P. Çalık, “Metabolik+genetik+biyokimyasal reaksiyon mühendisliği prensipleriyle rekombinant enzim üretimi,” 2008. Accessed: 00, 2020. [Online]. Available: