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Recent advances in the synthesis of fused heterocycles with new skeletons via alkyne cyclization

2020-06-11
Balcı, Metin
An account of our most recent developments on the synthesis of various fused heterocycles via alkyne cyclization is presented. The synthetic strategy involves N- or O-propargylation of heteroaromatic or aromatic compounds followed by intramolecular gold-catalyzed or NaH-promoted intramolecular cyclization reactions. This synthetic strategy represents a reasonable methodology for the construction of hitherto unknown skeletons. (C) 2020 Elsevier Ltd. All rights reserved.