Regioselective alkylation of dianions of cyclic 1.3-diketones via their monodimethylhydrazones. Synthesis of C-4 substituted cyclic 1.3-diketones

Date

1989-1

Author

Enders, Dieter
Demir, Ayhan Sıtkı

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Cyclic 1.3-diketones are transformed into the corresponding monodimethylhydrazones, which can be alkylated regioselectively at C-4 via dianions with various alkyl halides. The regioselective alkylation of cyclic 1.3-diketones 1, to 4-substituted derivatives 4 is described.

Subject Keywords

Biochemistry, Organic chemistry, Drug discovery

URI

https://hdl.handle.net/11511/51770

Journal

Tetrahedron Letters

DOI

https://doi.org/10.1016/s0040-4039(00)99560-1

Collections

Department of Chemistry, Article

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Citation Formats

D. Enders and A. S. Demir, “Regioselective alkylation of dianions of cyclic 1.3-diketones via their monodimethylhydrazones. Synthesis of C-4 substituted cyclic 1.3-diketones,” Tetrahedron Letters, pp. 1705–1708, 1989, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/51770.