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Regioselective alkylation of dianions of cyclic 1.3-diketones via their monodimethylhydrazones. Synthesis of C-4 substituted cyclic 1.3-diketones
Date
1989-1
Author
Enders, Dieter
Demir, Ayhan Sıtkı
Metadata
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Cyclic 1.3-diketones are transformed into the corresponding monodimethylhydrazones, which can be alkylated regioselectively at C-4 via dianions with various alkyl halides. The regioselective alkylation of cyclic 1.3-diketones 1, to 4-substituted derivatives 4 is described.
Subject Keywords
Biochemistry
,
Organic chemistry
,
Drug discovery
URI
https://hdl.handle.net/11511/51770
Journal
Tetrahedron Letters
DOI
https://doi.org/10.1016/s0040-4039(00)99560-1
Collections
Department of Chemistry, Article