Effect of doxorubicin loaded CS MNPs on cell proliferation in sensitive and doxorubicin resistant MCF-7 cell lines

Date

2014-09-01

Author

Unsoy, G.
Khodadust, R.
Yalcin, S.
Mutlu, Pelin
Pourianazar, N. Taghavi
Parsian, M.
Gündüz, Ufuk

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

91
views

0
downloads

URI

https://hdl.handle.net/11511/54167

Collections

Test and Measurement Center In advanced Technologies (MERKEZ LABORATUVARI), Conference / Seminar

Suggestions

OpenMETU
Core

Effect of doxorubicin on telomerase activity and apoptotic gene expression in doxorubicin-resistant and -sensitive MCF-7 cells Eskiocak, Ugur; Iseri, Ozlem Darcansoy; Kars, Meltem Demirel; Bicer, Atilla; Gündüz, Ufuk (2008-01-01) Background: Dose-and time-dependent effects of doxorubicin on telomerase activity ( TA) and expression levels of hTERT, Bcl-2, Bcl-x(L) and Bax were investigated in doxorubicin-resistant and -sensitive MCF-7 cells. Methods: Doxorubicin-resistant MCF-7/R was developed from sensitive MCF-7 breast carcinoma cell line and acquired resistance was demonstrated by XTT and mRNA analysis of MDR1 and MRP1 genes. Expression levels were determined by RT-PCR. Newly developed rapid and simple TRAP-silver staining assay w...
Effect of phytoestrogen emodin on doxorubicin-induced cytotoxicity and apoptosis on tumorigenic MCF-7 and non-tumorigenic MCF-10A human breast cells UYAR, PEMBEGÜL; KAYA, BURAK; Güray, Nülüfer Tülün (2014-09-01)
Effect of antioxidants on hepatic cytochrome P450 gene expressions in streptozotocin induced diabetes Sadi, G.; Güray, Nülüfer Tülün (2009-07-01)
Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells Donmez, Yaprak; Akhmetova, Laila; Iseri, Ozlem Darcansoy; Kars, Meltem Demirel; Gündüz, Ufuk (2011-04-01) One of the major problems of cancer chemotherapy is the development of multidrug resistance (MDR) phenotype. Among the numerous mechanisms of MDR, a prominent one is the increased expression of membrane transporter proteins, the action of which leads to decreased intracellular drug concentration and cytotoxicity of drugs. Among them, P-gp and MRP1, encoded by MDR1 and MRP1 genes, respectively, have been associated with MDR phenotype. Chemical modulators can be used to reverse MDR. These chemicals can either...
Effect of HHP on Microbial Inactivation and Conc of Lactoferrin, Lysozyme and B-Lactoglobulin in Donkey’s Milk Alpas, Hami; Köker, Alperen (null; 2018-10-26)

Citation Formats

G. Unsoy et al., “Effect of doxorubicin loaded CS MNPs on cell proliferation in sensitive and doxorubicin resistant MCF-7 cell lines,” 2014, vol. 281, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/54167.