Capacitive micromachined ultrasonic transducer arrays for integrated diagnostic/therapeutic catheters

Wong, Serena H.
Wygant, Ira O.
Yeh, David T.
Zhuang, Xuefeng
Bayram, Barış
Kupnik, Mario
Oralkan, Omer
Ergun, A. Sanli
Yaralioglu, Goksen G.
Khuri-Yakub, Butrus T.
In recent years, medical procedures have become increasingly non-invasive. These include endoscopic procedures and intracardiac interventions (e.g., pulmonary vein isolation for treatment of atrial fibrillation and plaque ablation for treatment of arteriosclerosis). However, current tools suffer from poor visualization and difficult coordination of multiple therapeutic and imaging devices. Dual-mode (imaging and therapeutic) ultrasound arrays provide a solution to these challenges. A dual-mode transducer can provide focused, noncontact ultrasound suitable for therapy and can be used to provide high quality real-time images for navigation and monitoring of the procedure. In the last decade, capacitive micromachined ultrasonic transducers (CMUTs), have become an attractive option for ultrasonic imaging systems due to their fabrication flexibility, improved bandwidth, and integration with electronics. The CMUT's potential in therapeutic applications has also been demonstrated by surface output pressures as high as 1 MPa peak to peak and continuous wave (CW) operation. This paper reviews existing interventional CMUT arrays, demonstrates the feasibility of CMUTs for high intensity focused ultrasound (HIFU), and presents a design for the next-generation CMUTs for integrated imaging and HIFU endoscopic catheters.
5th International Symposium on Therapeutic Ultrasound


Integrated circuit design for flip-chip bonded capacitive micromachined ultrasonic transducers
Maadi, Muhammad; Bayram, Barış; Department of Electrical and Electronics Engineering (2013)
In previous decades, the applications of ultrasound technologies in medical imaging and therapeutic systems have significantly increased. In conventional ultrasound systems, the transducer array is separated from the electronic instrumentation with multicore physical cabling. However, connection cables make the system too bulky and degrade the receive sensitivity in ultrasound 3D imaging applications because of the capacitance of long cables. The interface electronics for phased array ultrasound systems (im...
Development of a Visio-Haptic Integrated Dental Training Simulation System
Konukseven, Erhan İlhan; Önder, Mustafa Turgut; Mumcuoğlu, Ünal Erkan (2010-08-01)
The use of haptic devices in the medical field has become widespread in the last decade. In this study, a visio-haptic dental training system is developed using haptic and stereoscopic devices. Several advantages are offered by such a simulation system, including effective learning without any fear of making mistakes on a patient, possibility of repeating various dental operations, ease of evaluating student performance, and low-cost dental training even without an instructor. In this study, the biomechanic...
Understanding the Role of Polymer Surface Nanoscale Topography on Inhibiting Bacteria Adhesion and Growth
Liu, Luting; Ercan, Batur; Sun, Linlin; Ziemer, Katherine S.; Webster, Thomas J. (2016-01-01)
Catheter-associated infections, most of which are caused by microbial biofilms, are still a serious issue in healthcare and are associated with significant morbidity, mortality, and excessive medical costs. Currently, the use of nanostructured materials, especially materials with nano featured topographies, which have more surface area, altered surface energy, enhanced select protein adsorption, and selectively increased desirable cell functions while simultaneously decreasing competitive cell functions, se...
Terahertz pulsed imaging study of dental caries
Karagöz, Burcu; Altan, Hakan (2015-06-23)
Current diagnostic techniques in dentistry rely predominantly on X-rays to monitor dental caries. Terahertz Pulsed Imaging (TPI) has great potential for medical applications since it is a nondestructive imaging method. It does not cause any ionization hazard on biological samples due to low energy of THz radiation. Even though it is strongly absorbed by water which exhibits very unique chemical and physical properties that contribute to strong interaction with THz radiation, teeth can still be investigated ...
RHCS - A Clinical Recommendation System for Geriatric Patients
Beşik, İrem; Alpaslan, Ferda Nur (2018-08-31)
Medication errors caused by the mistakes of healthcare professionals are still one of the leading causes of death. The problem is even more serious with the elderly people suffering from multiple health problems at the same time. Clinical recommendation systems can be used to prevent such medication errors. In this paper, we present our clinical recommendation system (RHCS) which generates drug recommendations to assist healthcare professionals in making decisions on treatment process of geriatric patients....
Citation Formats
S. H. Wong et al., “Capacitive micromachined ultrasonic transducer arrays for integrated diagnostic/therapeutic catheters,” Boston, MA, 2006, vol. 829, Accessed: 00, 2020. [Online]. Available: