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Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase
Date
1999-12-17
Author
Demir, Ayhan Sıtkı
Dunnwald, T
Iding, H
Pohl, M
Muller, M
Metadata
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This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Aromatic aldehydes are converted into benzoins by benzoylformate decarboxylase catalyzed C-C bond formation. The reaction affords (R)-benzoins with high enantiomeric excess and in good chemical yields. A broad range of aromatic aldehydes can be used as substrates in aqueous buffer or buffer/DMSO-solutions.
Subject Keywords
ALPHA-HYDROXY KETONES
,
SILYL ENOL ETHERS
,
ENANTIOSELECTIVE OXIDATION
,
ACID DECARBOXYLASES
,
KINETIC RESOLUTION
,
PSEUDOMONAS-PUTIDA
,
BAKERS-YEAST
,
CONDENSATION
,
THIAZOLIUM
,
REDUCTION
URI
https://hdl.handle.net/11511/57349
Journal
TETRAHEDRON-ASYMMETRY
DOI
https://doi.org/10.1016/s0957-4166(99)00516-9
Collections
Department of Chemistry, Article
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A. S. Demir, T. Dunnwald, H. Iding, M. Pohl, and M. Muller, “Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase,”
TETRAHEDRON-ASYMMETRY
, pp. 4769–4774, 1999, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57349.