Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase

Date

1999-12-17

Author

Demir, Ayhan Sıtkı
Dunnwald, T
Iding, H
Pohl, M
Muller, M

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Aromatic aldehydes are converted into benzoins by benzoylformate decarboxylase catalyzed C-C bond formation. The reaction affords (R)-benzoins with high enantiomeric excess and in good chemical yields. A broad range of aromatic aldehydes can be used as substrates in aqueous buffer or buffer/DMSO-solutions.

Subject Keywords

ALPHA-HYDROXY KETONES, SILYL ENOL ETHERS, ENANTIOSELECTIVE OXIDATION, ACID DECARBOXYLASES, KINETIC RESOLUTION, PSEUDOMONAS-PUTIDA, BAKERS-YEAST, CONDENSATION, THIAZOLIUM, REDUCTION

URI

https://hdl.handle.net/11511/57349

Journal

TETRAHEDRON-ASYMMETRY

DOI

https://doi.org/10.1016/s0957-4166(99)00516-9

Collections

Department of Chemistry, Article

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Citation Formats

A. S. Demir, T. Dunnwald, H. Iding, M. Pohl, and M. Muller, “Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase,” TETRAHEDRON-ASYMMETRY, pp. 4769–4774, 1999, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57349.