Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
1SR,2SR,3SR,4RS,5RS,6RS,7SR,8RS)-7,8-dichlorobicyclo[4.2.0]octa-2,3,4,5-tetrayl tetraacetate
Date
2006-07-01
Author
Sahin, Ertan
Kelebekli, Latif
Kara, Yunus
Balcı, Metin
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
167
views
0
downloads
Cite This
In the title compound, C16H20Cl2O8, the bicyclic system contains a central non-planar cyclohexane ring which is fused to a cyclobutane moiety. The cyclohexane ring has a chair conformation and the whole system adopts a syn conformation. The structure provides information on the stereochemical course of the chlorination, photo-oxidation and hydroxylation steps of the reaction.
Subject Keywords
General Biochemistry, Genetics and Molecular Biology
,
General Medicine
URI
https://hdl.handle.net/11511/57486
Journal
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
DOI
https://doi.org/10.1107/s0108270106018336
Collections
Graduate School of Natural and Applied Sciences, Article
Suggestions
OpenMETU
Core
USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
Sapmaz, Aysegul; Berlin, Ilana; Bos, Erik; Wijdeven, Ruud H.; Janssen, Hans; Konietzny, Rebecca; Akkermans, Jimmy J.; Erson Bensan, Ayşe Elif; Koning, Roman; Kessler, Benedikt M.; Neefjes, Jacques; Ovaa, Huib (2019-03-29)
The endosomal system is a highly dynamic multifunctional organelle, whose complexity is regulated in part by reversible ubiquitylation. Despite the wide-ranging influence of ubiquitin in endosomal processes, relatively few enzymes utilizing ubiquitin have been described to control endosome integrity and function. Here we reveal the deubiquitylating enzyme (DUB) ubiquitin-specific protease 32 (USP32) as a powerful player in this context. Loss of USP32 inhibits late endosome (LE) transport and recycling of LE...
Synthesis, Characterization and Evaluation of Cytotoxic Activities of Novel Aziridinyl Phosphonic Acid Derivatives
Khan, Rehan; Ulusan, Sinem; Banerjee, Sreeparna; Doğan, Özdemir (Wiley, 2019-11-01)
New aziridine 2-phosphonic acids were prepared by monohydrolysis of the aziridine 2-phosphonates that were obtained by the modified Gabriel-Cromwell reaction of vinyl phosphonate or alpha-tosylvinyl phosphonate with a primary amine or a chiral amine. The cellular cytotoxicity of these compounds was tested against the HCT-116 colorectal cancer cell lines and the CCD-18Co normal colon fibroblast lines using the MTT assay. Three of the synthesized phosphonic acid derivatives 2e (ethyl hydrogen {(2S)-1-[(1S)-1-...
(2-Hydroxyethy1)hydraziniurn(2+) dichloride
Turgut, G; Zora, Metin; Odabasoglu, M; Ersanli, CC; Buyukgungor, O (International Union of Crystallography (IUCr), 2005-05-01)
The crystal structure of the title compound, C2H10N2O2+• 2Cl(-), is built up from one 2-hydroxyethylhydrazinium(2+) cation and two Cl- anions. The molecular structure is stabilized by O-H••• Cl and N-H••• Cl hydrogen bonds. The crystal structure is stabilized by one N-H••• O and three N-H••• Cl interactions, and the three-dimensional network of hydrogen bonds stabilizes the crystal packing. All five hydrazinium H atoms are involved in hydrogen...
Investigating the malleability of RNA aptamers
İlgü, Müslüm; Lamm, Monica H.; Nilsen-Hamilton, Marit (Elsevier BV, 2013-09-15)
Aptamers are short, single-stranded nucleic acids with structures that frequently change upon ligand binding and are sensitive to the ionic environment. To achieve facile application of aptamers in controlling cellular activities, a better understanding is needed of aptamer ligand binding parameters, structures, intramolecular mobilities and how these structures adapt to different ionic environments with consequent effects on their ligand binding characteristics. Here we discuss the integration of biochemic...
Zero-field nuclear magnetic resonance of chemically exchanging systems
Barskiy, Danila A.; Taylen, Michael C. D.; Marco-Rius, Irene; Kurhanewicz, John; Vigneron, Daniel B.; Çıkrıkcı, Sevil; Aydoğdu, Ayça; Reh, Moritz; Pravdivtsev, Andrey N.; Hoevener, Jan-Bernd; Blanchard, John W.; Wu, Teng; Budker, Dmitry; Pines, Alexander (Springer Science and Business Media LLC, 2019-07-05)
Zero- to ultralow-field (ZULF) nuclear magnetic resonance (NMR) is an emerging tool for precision chemical analysis. In this work, we study dynamic processes and investigate the influence of chemical exchange on ZULF NMR J-spectra. We develop a computational approach that allows quantitative calculation of J-spectra in the presence of chemical exchange and apply it to study aqueous solutions of [N-15]ammonium ((NH4+)-N-15) as a model system. We show that pH-dependent chemical exchange substantially affects ...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
E. Sahin, L. Kelebekli, Y. Kara, and M. Balcı, “1SR,2SR,3SR,4RS,5RS,6RS,7SR,8RS)-7,8-dichlorobicyclo[4.2.0]octa-2,3,4,5-tetrayl tetraacetate,”
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
, pp. 0–0, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57486.