Zinc perchlorate catalyzed one-pot amination-annulation of alpha-cyanomethyl-beta-ketoesters in water. Regioselective synthesis of 2-aminopyrrole-4-carboxylates

Date

2006-02-13

Author

Demir, Ayhan Sıtkı
Emrullahoglu, M

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In this paper, we report the efficient and regioselective synthesis of 2-aminopyrrole-4-carboxylates as derivatives of conformationally restricted analogues of gamma-amino butyrates (GABA) via a zinc perchlorate catalyzed amination-annulation of alpha-cyanomethyl-beta-ketoesters under mild reaction conditions in water.

Subject Keywords

Organic Chemistry, Biochemistry, Drug Discovery

URI

https://hdl.handle.net/11511/57774

Journal

TETRAHEDRON

DOI

https://doi.org/10.1016/j.tet.2005.11.018

Collections

Department of Chemistry, Article

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Citation Formats

A. S. Demir and M. Emrullahoglu, “Zinc perchlorate catalyzed one-pot amination-annulation of alpha-cyanomethyl-beta-ketoesters in water. Regioselective synthesis of 2-aminopyrrole-4-carboxylates,” TETRAHEDRON, pp. 1452–1458, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57774.