FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

DEVELOPMENT OF A MICRO-WELL-BASED MICROFLUIDIC 3D CELL CULTURE FOR CYTOTOXICITY ASSAYS Farahani, Sarah; Yıldırım, Ender; Özçelikkale, Altuğ; Department of Micro and Nanotechnology (2023-1-26) This thesis presents a micro-well-based microfluidic platform's design, optimization, simulation, and fabrication for 3D cell culture. This work aims to create a system suitable for monitoring cytotoxicity assays on isolated chambers. In this context, microfluidic systems are promising for screening cell response to drugs. Here, a PMMA-based and pipette-operated microfluidic device for cytotoxicity assay is presented. The platform is incorporated into a channel and micro-chamber attached to the sidewa...
FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ Akkaya, Mahinur; Dagvadorj, Bayantes(2014-12-31) GENE-FUNCTION ANALYSIS OF CANDIDATE EFFECTOR PROTEINS OF WHEAT STRIPE RUST PATHOGEN
Design and implementation of high fill factor structures on low-cost uncooled infrared sensors Ertürk, Ozan; Akın, Tayfun; Department of Electrical and Electronics Engineering (2015) This thesis presents the design and implementation steps of high fill factor structures for existing SOI diode low-cost microbolometer FPAs. Advancements in uncooled infrared detectors enable high performance military grade uncooled microbolometers as well as ultra-low-cost infrared imagers for civilian applications. The trend in uncooled microbolometers to reduce the pixel pitch has become increasingly significant to lower the cost of detector and system integration due to optics, and increase spatial reso...
FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ Akkaya, Mahinur; Mustafa, Zemran(2014-12-31) SITE DIRECTED MUTATIONS OF AN PLANT PATHOGEN EFFECTOR GENE FOR FUNCTIONAL ANALYSIS
Development of an integrated lab-on-a-chip (LOC) platform for multidrug effect analysis Atik, Ali Can; Külah, Haluk; Yıldırım, Ender; Department of Electrical and Electronics Engineering (2019) This thesis presents analysis, design, fabrication, and testing of microfluidic sub-units designed for a droplet-based multidrug analysis platform. The platform is integrated with normally closed electrostatically actuated microvalves to monitor cytotoxicity of anticancer drugs on single cancer cells encapsulated in microdroplets. Here, elucidation of cancer heterogeneity requires precise functional analysis at single-cell levels which can assist to select effective drug regimens for personalized chemothera...

Citation Formats

D. Keskin, “FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ,” 2014. Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/60437.