SYNTHESİS OF NEW PHOSPHONİC ACİD DRİVATİVES AND THEIR USE AS AN ORGANOCATALYSTS FOR ENANTİOSELECTİVE SYNTHESIS OF ORGANIC COMPOUNDS

Synthesis of 2,3-disubstituted thiophenes from ketoalkynes Vatansever, Erol Can; Balcı, Metin; Department of Chemistry (2013) Synthesis of thiophene containing compounds are of particular interest in synthetic organic chemistry. Besides the importance for synthetic organic chemistry, thiophene derivatives are used in applied research such as drug synthesis and study of functional materials. In this thesis, a new methodology for developing of 2,3-disubstituted thiophenes was developed. This methodology utilizes readily available compounds in a two-step synthesis to provide a facile access to the 2,3-disubstituted thiophenes. In the...
Synthesis of New Squaramide Based Organocatalyst and Its Application for Enantioselective Synthesis of Organic Compounds Özdemir, Özge; Doğan, Özdemir; Department of Chemistry (2022-9-19) Organocatalytic asymmetric synthesis of organic compounds is one of the important fields of synthetic organic chemistry. Organocatalysts are small chiral organic molecules having certain functional groups, such as hydroxy, amino, amido etc. These catalysts are environmentally more friendly than the alternative chiral metal catalysts. Therefore, they are more popular and studied more than the metal catalysts. On the other hand, there are no organocatalysts that work well for every organic reaction. Here in t...
Synthesis of New Thienylene Pyrrole Monomers and Their Electropolymerizations Eken, Serap; Carbas, Buket Bezgin; Akdağ, Akın; Önal, Ahmet Muhtar (The Electrochemical Society, 2014-01-01) In this study, four new 2,5-dithienylpyrroles (SNS) 1-(3-fluoro-phenyl)-2,5-di(thiophen-2-yl)-1H-pyrrole (m-FPTP), 1-(3-chlorophenyl)-2,5-di(thiophen-2-yl)-1H-pyrrole (m-ClPTP), 1-(3-bromo-phenyl)-2,5-di(thiophen-2-yl)-1H-pyrrole (m-BrPTP) and 1-(4-bromo-phenyl)-2,5-di(thiophen-2-yl)-1H-pyrrole (p-BrPTP) containing meta and para substituted benzene ring at the nitrogen atom were synthesized via Paal-Knorr condensation of 1,4-di(2-thienyl)-1,4-butanedione with corresponding halo-substituted anilines. The mon...
Synthesis of Functionalized Novel alpha-Amino-beta-alkoxyphosphonates through Regioselective Ring Opening of Aziridine-2-phosphonates Polat-Cakir, Sidika; Beksultanova, Nurzhan; Doğan, Özdemir (Wiley, 2019-11-01) Aziridines are highly useful compounds as building blocks for the synthesis of important organic compounds. Amino acid synthesis by aziridine ring opening reaction is a good example to the use of aziridines. Although this reaction is studied by many groups, the synthesis of amino phosphonic acids is less explored. In this study, we have carried out the ring opening reaction of aziridinyl phosphonates with a variety of alcohols including the more functional propargylic and allylic alcohols. These reactions p...
Synthesis of chiral lactones via the baeyer villiger oxidation of cyclic aromatic acetoxy ketones novel annulation reactions of 2-propynyl-1,3-dicarbonyl compounds to form pyrroles addition of acyl phosphonates to diethyl cyanophosphonate (depc) Aybey, Asuman; Demir, Ayhan Sıtkı; Department of Chemistry (2009) Chiral Baeyer-Villiger (BV) oxidation of cyclic ketones allows rapid access to asymmetric lactones as valuable intermediates in organic chemistry and frequently encountered precursors in enantioselective synthesis. In the first part, BV oxidation of functionalized ketones, especially cyclic -hydroxy and acetoxy ketones is described which could be a straightforward route to the -hydroxy lactones and -hydroxyalkanoic acid derivatives. The -acetoxylation of indanone, tetralone and chromanone derivatives by usi...

Citation Formats

Ö. Doğan, “SYNTHESİS OF NEW PHOSPHONİC ACİD DRİVATİVES AND THEIR USE AS AN ORGANOCATALYSTS FOR ENANTİOSELECTİVE SYNTHESIS OF ORGANIC COMPOUNDS,” 2017. Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/61210.