Quantitative structure-activity relationship study of some 7-substituted theophyllines

Date

1998-01-01

Author

Türker, Burhan Lemi
Akgun, H
Balkan, A

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Some novel 7-substituted theophylline derivatives have been investigated for quantitative structure-activity relationship (QSAR). For this purpose, their bronchodilatory activities (in vitro), which were examined by the inhibition of acetylcholine induced contraction in tracheae isolated from guinea pigs, have been correlated with various quantum chemical and physicochemical parameters.

Subject Keywords

Aminophylline, Quantitative structure-activity relationships, Theophylline

URI

https://hdl.handle.net/11511/62860

Journal

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH

Collections

Department of Chemistry, Article

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Citation Formats

B. L. Türker, H. Akgun, and A. Balkan, “Quantitative structure-activity relationship study of some 7-substituted theophyllines,” ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, pp. 39–42, 1998, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/62860.