Possible interactions between antioxidant enzymes and free sialic acids in saliva: A preliminary study on elite judoists

Cavas, L
Arpinar, P
Yurdakoc, K
Measurement of antioxidant enzyme activities is of great importance in the evaluation of oxidative stress in human metabolism. Sialic acids are also vital bio-markers for some diseases such as acute myocardial infarction and diabetes. In the present study, antioxidant enzyme activities (SOD, CAT, GSH-Px) and free sialic acid (FSA) levels in saliva were determined before and after training in the elite Turkish judoists (ETJ). According to the results, antioxidant enzyme activities in post-exercise values were significantly (p < 0.05) higher than those of pre-exercise values. A major finding of this study was that FSA levels also increased significantly (p < 0.05). Superoxide radical anion might have been effectively dismutated to hydrogen peroxide by elevated SOD activity. Accordingly, it suggests that CAT, having a higher increasing rate, was more efficient than GSH-Px in decomposition of hydrogen peroxide. In conclusion, the increase in antioxidant enzyme activities might have caused the elevation of FSA levels after training. Over-excreted sialic acids to saliva might have an important role in the removal of hydrogen peroxide. Since the increase in FSA levels in saliva has been found to be in well accordance with antioxidant enzymes, FSA may be concluded as an alternative oxidative stress marker in athletes.


Impact of Social-Ecologic Intervention on Physical Activity Knowledge and Behaviors of Rural Students
CENGİZ, CEVDET; İnce, Mustafa Levent (Human Kinetics, 2014-11-01)
Background: The purpose of the study was to determine the effects of a social-ecologic intervention on health-related fitness (HRF) knowledge and behaviors of students (n = 62) living in rural areas. Methods: A prepost test control group design was constructed. In addition, qualitative data were collected by focus group discussions in the experimental group. Physical activity environment of a middle school was changed based on the social-ecologic model (SEM) with a focus on intrapersonal, interpersonal, com...
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The oxygenation of polyunsaturated fatty acids such as arachidonic and linoleic acid through lipoxygenases (LOXs) and cyclooxygenases (COXs) leads to the production of bioactive lipids that are important both in the induction of acute inflammation and its resolution. Amongst the several isoforms of LOX that are expressed in mammals, 15-LOX-1 was shown to be important both in the context of inflammation, being expressed in cells of the immune system, and in epithelial cells where the enzyme has been shown to...
Paraoxonase/arylesterase ratio, PON1 192Q/R polymorphism and PON1 status are associated with increased risk of ischernic stroke
Demirdogen, Birsen Can; Turkanoglu, Aysun; Bek, Semai; Sanisoglu, Yavuz; Demirkaya, Seref; Vural, Okay; Arinc, Emel; Adalı, Orhan (Elsevier BV, 2008-01-01)
Objectives: In recent years, importance of enzyme activity measurements, in addition to genotyping, in epidemiological studies relating paraoxonase 1 (PON1) and vascular disease was emphasized. This is the first report evaluating paraoxonase and arylesterase activities as risk factors for ischemic stroke. In addition, PON1 192Gln(Q)/Arg(R) and 55Leu(L)/Met(M) polymorphisms were also analyzed.
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Canli, Secil Demirkol; Seza, Esin Gulce; Sheraj, Ilir; Gomceli, Ismail; Turhan, Nesrin; Carberry, Steven; Prehn, Jochen H. M.; GÜRE, ALİ OSMAY; Banerjee, Sreeparna (Oxford University Press (OUP), 2020-09-01)
AKR1B1 and AKR1B10, members of the aldo-keto reductase family of enzymes that participate in the polyol pathway of aldehyde metabolism, are aberrantly expressed in colon cancer. We previously showed that high expression of AKR1B1 (AKR1B1(HIGH)) was associated with enhanced motility, inflammation and poor clinical outcome in colon cancer patients. Using publicly available datasets and ex vivo gene expression analysis (n = 51, Ankara cohort), we have validated our previous in silico finding that AKR1B1(HIGH) ...
Gene expressions of Mn-SOD and GPx-1 in streptozotocin-induced diabetes: effect of antioxidants
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Increased oxidative stress and impaired antioxidant defense mechanisms are believed to be the important factors contributing to the pathogenesis and progression of diabetes mellitus. In this study, we have reported the effects of the streptozotocin-induced diabetes on the gene expression and the activities of two antioxidant enzymes, manganese superoxide dismutase (MnSOD) and glutathione peroxidase (GPx). We also studied the effects of two antioxidants, vitamin C and DL-alpha-lipoic acid (LA), on the system...
Citation Formats
L. Cavas, P. Arpinar, and K. Yurdakoc, “Possible interactions between antioxidant enzymes and free sialic acids in saliva: A preliminary study on elite judoists,” INTERNATIONAL JOURNAL OF SPORTS MEDICINE, pp. 832–835, 2005, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/67033.