Date

2010-01-01

Author

Baysoy, Engin
Cunedioglu, Ugur
Yilmaz, Buelent

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A multielectrode basket-shaped contact catheter (MBC) provides simultaneous recordings of unipolar or bipolar electrograms from within the heart chambers Another catheter-based mapping approach uses the multielectrode intravenous catheters (MIVCs), which are widely used to diagnose and treat supraventricular arrhythmias It is also known that mapping techniques are usually limited to one surface at a time Therefore, an approach that can be used for simultaneous mapping of left and right endocardial surfaces and epicardial surface will be beneficial to characterize and discriminate the endocardial and epicardial sources of the arrhythmias more accurately In this study, we used statistical estimation method to map the endocardial and epicardial surfaces simultaneously based on combined usage of the MBC and MIVC The statistical estimation method is based on high-resolution training data set to hypothesize the relationship between catheter measurements and inaccessible sites To test tills approach, we created a high-resolution map database consisting of computer simulation results of Aliev-Panfilov model of cardiac electrical activity on 3-dimensional Auckland canine heart geometry The simulation database included 2590 maps each paced from a unique endocardial or epicardial site Fifty or five percent of the database was used as the training data set and the remaining as test data set in the statistical estimation procedure We selected 64 sites on the left and 64 on the right endocardial surfaces of the model heart geometry and used them as the surrogate MBC measurement sites Ninety-one sites on the meal-Mum corresponding to the major coronary veins served as the surrogate MIVC leads Finally, we tested the success of the method to determine the source of the arrhythmias using the correlation coefficient between the original and estimated activation maps and linear distance between their earliest activated sites The performance of this approach was promising, such as when MBC: on the left endocardium and MIVC were used to:tether, the average linear distance was similar to 2 4 mm and mean correlation coefficient was 0 995 It was possible to locate 95% of epicardial arrhythmia cases correctly, on the epicardium Ninety-nine percent of left endocardially originating arrhythmias were correctly located on the left endocardium The results of this study showed that this approach is feasible and requires further effort (C) 2010 Elsevier Inc All rights reserved

Subject Keywords

Cardiology and Cardiovascular Medicine

URI

https://hdl.handle.net/11511/67085

Collections

Department of Biology, Article