SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME NEW BENZIMIDAZOLE DERIVATIVES

Date

1991-05-01

Author

GOKER, H
ERTAN, R
AKGUN, H
YULUG, N

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Synthesis and antifungal evaluation of 5-ethoxycarbonyl-2-(substituted-benzyl or phenoxymethyl)benzimidazoles are reported. Structures of the compounds were elucidated with IR-, H-1-NMR-, C-13-NMR-, mass-spectra and elemental analysis. Preliminary results show that none of the synthesized benzimidazole derivatives has antifungal activity at the concentration of 100-mu-g/ml against Candida parapsilosis, Candida stellatoidea, and Candida pseudotropicalis.

Subject Keywords

Drug Discovery, Pharmaceutical Science

URI

https://hdl.handle.net/11511/67526

Journal

ARCHIV DER PHARMAZIE

DOI

https://doi.org/10.1002/ardp.19913240505

Collections

Department of Chemistry, Article

Citation Formats

H. GOKER, R. ERTAN, H. AKGUN, and N. YULUG, “SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME NEW BENZIMIDAZOLE DERIVATIVES,” ARCHIV DER PHARMAZIE, vol. 324, no. 5, pp. 283–286, 1991, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/67526.