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Water-soluble green perylenediimide (PDI) dyes as potential sensitizers for photodynamic therapy
Date
2005-07-07
Author
Yukruk, F
Dogan, AL
Canpinar, H
Guc, D
Akkaya, EU
Metadata
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This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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A series of water-soluble green perylenediimide (PDI) dyes have been synthesized. On red light excitation, these dyes were shown to be efficient generators of singlet oxygen, and in cell culture media, they were shown to display significant light-induced cytotoxic effects on the human erythroleukemia cell line (K-562). It appears that highly versatile PDI dyes are likely to find new applications in photodynamic therapy.
Subject Keywords
Physical and Theoretical Chemistry
,
Organic Chemistry
,
Biochemistry
URI
https://hdl.handle.net/11511/67927
Journal
ORGANIC LETTERS
DOI
https://doi.org/10.1021/ol050841g
Collections
Department of Chemistry, Article