Rapid multi-orientation quantitative susceptibility mapping

Date

2016-01-15

Author

Bilgic, Berkin
Xie, Luke
Dibb, Russell
Langkammer, Christian
Mutluay, Aysegul
Ye, Huihui
Polimeni, Jonathan R.
Augustinack, Jean
Liu, Chunlei
Wald, Lawrence L.
Setsompop, Kawin

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

138
views

0
downloads

Three-dimensional gradient echo (GRE) is the main workhorse sequence used for susceptibility weighted imaging (SWI), quantitative susceptibility mapping (QSM), and susceptibility tensor imaging (STI). Achieving optimal phase signal-to-noise ratio requires late echo times, thus necessitating a long repetition time (TR). Combined with the large encoding burden of whole-brain coverage with high resolution, this leads to increased scan time. Further, the dipole kernel relating the tissue phase to the underlying susceptibility distribution undersamples the frequency content of the susceptibility map. Scans at multiple head orientations along with calculation of susceptibility through multi-orientation sampling (COSMOS) are one way to effectively mitigate this issue. Additionally, STI requires a minimum of 6 head orientations to solve for the independent tensor elements in each voxel. The requirements of high-resolution imaging with long TR at multiple orientations substantially lengthen the acquisition of COSMOS and STI. The goal of this work is to dramatically speed up susceptibility mapping at multiple head orientations. We demonstrate highly efficient acquisition using 3D-GRE with Wave CAIPI and dramatically reduce the acquisition time of these protocols. Using R = 15-fold acceleration with Wave-CAIPI permits acquisition per head orientation in 90 s at 1.1 mm isotropic resolution, and 5: 35 min at 0.5 mm isotropic resolution. Since Wave-CAIPI fully harnesses the 3D spatial encoding capability of receive arrays, the maximum g-factor noise amplification remains below 1.30 at 3T and 1.12 at 7T. This allows a 30-min exam for STI with 12 orientations, thus paving the way to its clinical application.

Subject Keywords

Cognitive Neuroscience, Neurology

URI

https://hdl.handle.net/11511/68573

Journal

NEUROIMAGE

DOI

https://doi.org/10.1016/j.neuroimage.2015.08.015

Collections

Department of Architecture, Article

Suggestions

OpenMETU
Core

Identification of nonlinear features in cortical and subcortical signals of Parkinson's Disease patients via a novel efficient measure Özkurt, Tolga Esat; Zrinzo, Ludvic; Limousin, Patricia; Foltynie, Tom; Oswal, Ashwini; Litvak, Vladimir (Elsevier BV, 2020-12-01) This study offers a novel and efficient measure based on a higher order version of autocorrelative signal memory that can identify nonlinearities in a single time series. The suggested method was applied to simultaneously recorded subthalamic nucleus (STN) local field potentials (LFP) and magnetoencephalography (MEG) from fourteen Parkinson's Disease (PD) patients who underwent surgery for deep brain stimulation. Recordings were obtained during rest for both OFF and ON dopaminergic medication states. We ana...
Encoding the local connectivity patterns of fMRI for cognitive task and state classification Ertugrul, Itir Onal; Ozay, Mete; Yarman Vural, Fatoş Tunay (Springer Science and Business Media LLC, 2019-08-01) In this work, we propose a novel framework to encode the local connectivity patterns of brain, using Fisher vectors (FV), vector of locally aggregated descriptors (VLAD) and bag-of-words (BoW) methods. We first obtain local descriptors, called mesh arc descriptors (MADs) from fMRI data, by forming local meshes around anatomical regions, and estimating their relationship within a neighborhood. Then, we extract a dictionary of relationships, called brain connectivity dictionary by fitting a generative Gaussia...
Multi-Physics Multi-Contrast Magnetic Resonance Imaging Eyüboğlu, Behçet Murat; Sadighi, Mehdi (2021-05-15) In this study, a Diffusion-Weighted (DW) Spin Echo (SE) based pulse sequence with current injection is proposed to combine data acquisitions of theDiffusion Tensor (), current-induced magnetic flux densityand the magnetohydrodynamic (MHD) flow imaging. The current density distribution() can be estimated from the measuredusing the MRCDI method and the conductivity tensor can be reconstructed from the acquiredand theestimatedusing the DT-MREIT method. The acquired results of an experimental phantom with aniso...
Preparation and thermal characterization of poly(2-vinylpyridine) copolymers coordinated to Cr nanoparticles Öztürk, Yurdagül; Kayran, Ceyhan; Hacaloğlu, Jale (2015-06-01) In this study, polystyrene-block-poly(2-vinylpyridine), PS-b-P2VP, polyisoprene-block-poly(2-vinylpyridne), PI-b-P2VP and poly(methyl metacrylate)-block-poly(2-vinylpyridine), PMMA-b-P2VP, coordinated to Cr metal were synthesized and characterized by Fourier transform infrared, transmission electron microscopy and direct pyrolysis mass spectrometry techniques. Both thermal degradation mechanism and thermal stability of P2VP blocks were affected by the coordination of Cr nanoparticles to nitrogen of pyridine...
Fast automatic scanning system for emulsion experiments Kılınç, Cemali; Hosseını, Behzad; Kamışçıoğlu, Mustafa; Güler, Ali Murat; Öcalan, Kadir; Tufanlı, Serhan; Altınok, Özgür(2012) Hızlı emülsiyon tarama sistemi, Nükleer emülsiyon tekniğinin kullanıldığı deneylerde veri alımı ve işlenmesininde kullanılmaktadır. Nükleer emülsiyon tekniği geçmişte mikron hassasiyeti gerektiren araştırmalarda başarıyla uygulanmış bir çok keşif bu tekniğin uygulanması sonucunda yapılmıştır. Örneğin 1947 C. Powel'ın Pion'u nükleer emülsiyon tekniğini kullanarak keşfetmiştir. Günümüzde ise nükleer emülsiyon tekniğinin en büyük çapta uygulandığı proje OPERA deneyidir. OPERA...

Citation Formats

B. Bilgic et al., “Rapid multi-orientation quantitative susceptibility mapping,” NEUROIMAGE, pp. 1131–1141, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/68573.