Bioactivities of novel boehmeriasin derivatives in liver cancer cells

Akhan Guzelcan, Ece
Bauman, Marcus
Baxendale, IAN
Atalay, Rengül


Bioactivities of novel boehmeriasin derivatives in liver cancer cells
Guzelcan, E. Akhan; Baumann, M.; Baxendale, I.; Atalay, Rengül (2016-07-01)
Bioactivity Of Protoiurus Kraepelini Scorpione Iuridae Venom
Doğan, Tuğba; Selin, Gerekçi; Hazal, Hüsnügil; İzbırak, Afife; Özen, Can (2016-01-12)
Bioactivity analysis of novel indole derivatives on hepatocellular carcinoma as sirtuin inhibitors
Bınarcı, Büşra; Muyan, Mesut; Kahraman, Deniz Cansen; Department of Molecular Biology and Genetics (2021-9-8)
Hepatocellular carcinoma is ruthless cancer, a subtype of primary liver cancer and affects many people with various ethnic backgrounds and age intervals. Indole derivative molecules are potent chemicals used in several drugs and target many essential proteins malfunctioning multiple diseases. One of the targets of indole derivatives is histone deacetylases (HDACs), which reverses histone acetylation modifications that open DNA to lead transcription machinery to promote transcription. This study screened 28 ...
Bioactive agent carrying PLGA nanoparticles in the treatment of skin diseases
Küçükturhan, Aysu; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat; Department of Biomedical Engineering (2012)
The aim of this study was to develop drug delivery system based on poly(lactic acid-co-glycolic acid) (PLGA) nanoparticles (NPs) to achieve personalized treatment of selected skin disorders, like photo-aging, psoriasis and atopic dermatitis. Dead Sea Water (DSW) and Retinyl Palmitate (RP) were used as active agents and they were loaded in PLGA NPs prepared either as spheres or capsules by o/w or w/o/w methods. MgCl2 and bovine serum albumin (BSA) served as model active compounds. The diameter of the NPs was...
Biomimetic preparation of HA precursors at 37 degrees C in urea- and enzyme urease-containing synthetic body fluids
Bayraktar, D; Tas, AC (1999-12-01)
An important inorganic phase of synthetic bone applications, calcium hydroxyapatite (HA, Ca-10(PO4)(6)(OH)(2)), was prepared as a single-phase and sub-micron bioceramic powder. Carbonated HA precursors were synthesized from calcium nitrate tetrahydrate and diammonium hydrogen phosphate salts dissolved in "synthetic body fluid" (SBF) solutions, containing urea (H2NCONH2) and enzyme urease, under the biomimetic conditions of 37 degrees C and pH 7.4, by using a novel chemical precipitation technique.
Citation Formats
E. Akhan Guzelcan, M. Bauman, I. Baxendale, and R. Atalay, “Bioactivities of novel boehmeriasin derivatives in liver cancer cells,” 2016, vol. 61, Accessed: 00, 2020. [Online]. Available: