Bioactivities of novel boehmeriasin derivatives in liver cancer cells

Guzelcan, E. Akhan
Baumann, M.
Baxendale, I.
Atalay, Rengül


APA isoform diversity in triple negative breast cancers
AKMAN TUNCER, HESNA BEGÜM; ÖYKEN, MERVE; AĞUŞ, HIZLAN HINCAL; Erdem, Murat; Çiçek, Esra; Can, Tolga; Erson Bensan, Ayşe Elif (2017-04-05)
Alternative polyadenylation (APA) plays a role in gene expression regulation generally by shortening of 3'UTRs and relieving microRNA-mediated repression. Therefore, APA is gaining increased attention as a potential mechanism to activate oncogenes. Owing to high proliferative indices of triple negative breast cancers (TNBCs), we hypothesized APA to cause 3'UTR length changes in this aggressive subgroup of breast cancers. Our probe-based meta-analysis approach identified 3'UTR length alterations where the si...
Electrochemical and chemical oxidation of K(C2H5OCS2),[Ni(C2H5OCS2)(2)] and [N(C2H5)(4)][Ni(C2H5OCS2)(3)]
Dag, O; Önal, Ahmet Muhtar; Isci, H (1996-06-26)
Electrochemical and chemical oxidation of (Et-Xan(-)), [Ni(Et-Xan)(2)] and [Ni(Et-Xan)(3)](-) (Et-Xan(-) = C2H5OCS2- have been studied by Cyclic Voltammetry and in situ UV-Vis spectroscopy in acetonitrile at room temperature. Cyclic Voltammograms (CV) of Et-Xan(-) and Ni(Et-Xan)(2) display one (0.00 V) and two (0.35 and 0.80 V) irreversible oxidation peaks, respectively, referenced to Ag/Ag+(0.10 M) electrode. However, CV of Ni(Et-Xan)(3)(-) displays one reversible (-0.15 V) and two irreversible (0.35, 0.80...
Investigation of a mechanistic link between 15-Lipoxygenase-1 (15-LOX-1) and Metastasis Associated Protein 1 (MTA1) in human colorectal carcinoma cell lines
ÇAĞATAY, SİBEL; Banerjee, Sreeparna (2013-09-01)
Background: Metastasis Associated Protein 1 (MTA1) is a member of the nuclear remodeling and histone deacetylase (NuRD) complex that is known to repress the expression of several tumor suppressor genes. 15-lipoxygenase-1 (15-LOX-1), a member of the inflammatory eicosanoid pathway, has been shown by us and others to have an anti-tumorigenic role in colon cancer. ALOX15 was recently shown to be repressed by the NuRD complex. Previously we have reported that ectopic expression of 15-LOX-1 in colon cancer cells...
Fully Integrated Ultra-Low Voltage DC-DC Converter with Voltage Quadrupling LC Tank Oscillator for Energy Harvesting Applications
Jayaweera, H. M. P. C.; Tabrizi, Hamed Osouli; Muhtaroglu, Ali (2017-12-02)
This paper presents a novel fully integrated ultra-low voltage DC-DC converter and its multi-stage architecture. DC-DC converter frequency has been analytically derived using model analysis and validated in Cadence environment. The proposed voltage quadrupling LC tank oscillator eliminates the buffer circuits utilized in the traditional DC-DC converter, hence improves the performance metrics such as efficiency and output power capacity. The circuit was designed in 180nm standard CMOS process and was simulat...
Regioselectivity in the Ene reaction of singlet oxygen with cyclic alkenes and application of Ene reaction to stereoselective synthesis of carbaheptopyranose derivatives
Doğan, Şengül Dilem; Balcı, Metin; Department of Chemistry (2010)
In the first part of this thesis is related to the regioselectivity in ene reaction of singlet oxygen with cyclic alkenes. The photooxygenation of 1-methyl-, 2,3-dimethyl-, 1,4-dimethylcyclohexa-1,4-dienes, 1,2,3,4,5,8-hexahydronaphthalene (16) and 2,3,4,7-tetrahydro-1H-indene (17) which are readily available through Birch reduction, yielded the ene products. The formed endocyclic dienes were trapped by the addition of singlet oxygen to give corresponding bicyclic endoperoxy-hydroperoxides. In the case of 1...
Citation Formats
E. A. Guzelcan, M. Baumann, I. Baxendale, and R. Atalay, “Bioactivities of novel boehmeriasin derivatives in liver cancer cells,” EUROPEAN JOURNAL OF CANCER, pp. 0–0, 2016, Accessed: 00, 2020. [Online]. Available: