Building Dicer1 regulation network of mouse liver hepatocytes

Ünsal, Şeyma
Beyge, Mahmut
Aydın Son, Yeşim
RNA induced gene silencing complex (RISC) has a role in many cellular processes which includes regulation of gene expression, immune response, cell differentiation and embryonic development. Dicer protein is a key regulator of these processes. Dicer1 specifically has central role in maturation of RISC substrate RNA and RISC assembly in mouse. Here the results of a microarray study that investigates the molecular level changes in dicer1 knockout mouse liver hepatocytes is re-analysed and the differentially regulated genes are hierarchically clustered based on molecular function and co-expression to construct the suggested regulation network of Dicer1 in mouse hepatocytes. © 2012 IEEE.


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Citation Formats
Ş. Ünsal, M. Beyge, and Y. Aydın Son, “Building Dicer1 regulation network of mouse liver hepatocytes,” 2012, Accessed: 00, 2020. [Online]. Available: