The Effect of Alternative Splicing on Tumor Specific Protein Networks



The Role of NEK6 gene expression in multidrug resistance and apoptosis in MCF-7 and K-562 cell lines
Nabioğlu, Ayça; Gündüz, Ufuk; Mutlu, Pelin; Department of Biology (2015)
Grey mold disease is one of these postharvest decays. Especially grapes are infected by Botrytis cinerea known as a causal agent of the grey mold disease. Some fungicides are used to control this disease. However, they cause funcide- resistant strains of the pathogens and make hazardous for human health and environmental safety. Therefore, The killer yeasts are considered as promising alternative antifungal agents among other biocontrol agents. Pichia anomala which is a killer yeast secretes the K5 type yea...
The Role of Nek 6 Gene Expression in Multidrug Resistance and Apoptosis in MCF 7 and K 562 Cell Lines
Ayça, Nabioğlu; Pelin, Mutlu; Yalçın Azarkan, Serap; Gündüz, Ufuk (null; 2015-06-20)
The Effect of vitamin D2 on phospholipid model membranes and protein-lipid interactions
Eker, Fatma; Severcan, Feride; Department of Biology (1997)
Culfa, Şeyda; Son, Çağdaş Devrim; Bek, Alpan; Department of Biochemistry (2022-8-29)
Cells' interaction with their environment and how their responses to different mechanical cues are regulated have attracted attention for decades. These mechanical cues vary from topography to substrate stiffness. Knowing how topography-induced cell responses are regulated might give useful information about cell behaviors in health and disease states. This knowledge can be utilized to manipulate cell behaviors for different purposes. Topography-dependent cell behaviors rely on various parameters such as ce...
The Role of AKR1B10 in Oxidative Stress Response in Hepatocellular Carcinoma
Tuğral, Hoşnaz; Banerjee, Sreeparna; Department of Biology (2022-2-8)
Hepatocellular carcinoma (HCC) is projected to account for 4.7 percent of all new cancer cases and 8.2 percent of all cancer-related deaths globally. NADPH- dependent aldoketoreductases (AKRs) can reduce carbonyl substrates like glucose, sugar aldehydes, keto-steroids, keto-prostaglandins, retinals, quinones, and lipid peroxidation by-products. A member of this family of enzymes, AKR1B10, is thought to be a robust early marker for HCC as well as a predictor of poor prognosis. Oxidative stress in cells may r...
Citation Formats
H. C. Demirel and N. Tunçbağ, “The Effect of Alternative Splicing on Tumor Specific Protein Networks,” 2017, Accessed: 00, 2021. [Online]. Available: