Optimal Control of convective FitzHugh Nagumo model

2015-06-29
Karasözen, Bülent
Güney , Tuğba
In this talk we investigate optimal control of wave propagation in excitable media described by two-dimensional FitzHugh-Nagumo model. The model consists of two coupled reaction-diffusionconvection equations describing the flow in blood coagulation and in bioreactors [2] ∂u ∂t = du∆u − V (y) ∂u ∂x + αu(u − β)(1 − u) − v, ∂v ∂t = dv∆v − V (y) ∂v ∂x + (γu − v), where u and v are activator and inhibitor, respectively and V (y) is the velocity profile. The flow plays an important role by the regularization of the excitation threshold and wave propagation. The plane waves occurring in two-dimensional media are controlled in different ways. We solve optimal control problem using the all-at-once approach and sparse [1] and H1 regularized [3] controls. For space discretization we use the symmetric interior penalty discontinuous Galerkin method [4] and for time discretization the implicit Euler method.
27th IFIP TC7 Conference 2015 onSystem Modelling and Optimization, (29 June - 03 July 2015)

Suggestions

Optimal control of convective FitzHugh-Nagumo equation
Uzunca, Murat; Kucukseyhan, Tugba; Yücel, Hamdullah; Karasözen, Bülent (2017-05-01)
We investigate smooth and sparse optimal control problems for convective FitzHugh Nagumo equation with traveling wave solutions in moving excitable media. The cost function includes distributed space time and terminal observations or targets. The state and adjoint equations are discretized in space by symmetric interior point Galerkin (SIPG) method and by backward Euler method in time. Several numerical results are presented for the control of the traveling waves. We also show numerically the validity of th...
Ensemble Modeling of Hydrologic and Hydraulic Processes at One Shot: Application to Kinematic Open-Channel Flow under Uncertain Channel Properties by the Stochastic Method of Characteristics
Ercan, Ali; Kavvas, M. L. (2012-01-01)
A stochastic kinematic wave model for open-channel flow under uncertain channel properties is developed. The Fokker-Planck equation (FPE) of the kinematic open-channel flow process under uncertain channel properties is developed by using the method of characteristics. Every stochastic partial differential equation has a one-to-one relationship with a nonlocal Lagrangian-Eulerian FPE (LEFPE). As such, one can develop an LEFPE for the governing equation of any hydrologic or hydraulic process as the physically...
Optimal Power Allocation for Average Detection Probability Criterion Over Flat Fading Channels
Sarıtaş, Serkan; Sezer, Ahmet Dundar; Gezici, Sinan; Yuksel, Serdar (2017-03-01)
In this paper, the problem of optimal power allocation over flat fading additive white Gaussian noise channels is considered for maximizing the average detection probability of a signal emitted from a power constrained transmitter in the Neyman-Pearson framework. It is assumed that the transmitter can perform power adaptation under peak and average power constraints based on the channel state information fed back by the receiver. Using results from measure theory and convex analysis, it is shown that this o...
Stochastic modeling of biochemical systems with filtering and smoothing
Haksever, Merve; Uğur, Ömür; Department of Scientific Computing (2019)
Deterministic modeling approach is the traditional way of analyzing the dynamical behavior of a reaction network. However, this approach ignores the discrete and stochastic nature of biochemical processes. In this study, modeling approaches, stochastic simulation algorithms and their relationships to each other are investigated. Then, stochastic and deterministic modeling approaches are applied to biological systems, Lotka-Volterra prey-predator model, Michaelis-Menten enzyme kinetics and JACK-STAT signalin...
Ensemble Modeling of Hydrologic and Hydraulic Processes at One Shot: Application to Kinematic Open-Channel Flow under Uncertain Channel Properties and Uncertain Lateral Flow Conditions by the Stochastic Method of Characteristics
Ercan, Ali; Kavvas, M. L. (2012-03-01)
A stochastic kinematic wave model for open channel flow is developed under uncertain channel properties and uncertain lateral flow conditions. Applying a known methodology, the Fokker-Planck equation (FPE) of the kinematic open-channel flow process under uncertain channel properties and uncertain lateral flow conditions is derived using the method of characteristics. Because every stochastic partial differential equation has a one-to-one relationship with a nonlocal Lagrangian-Eulerian Fokker-Planck equatio...
Citation Formats
B. Karasözen and T. Güney, “Optimal Control of convective FitzHugh Nagumo model,” presented at the 27th IFIP TC7 Conference 2015 onSystem Modelling and Optimization, (29 June - 03 July 2015), France, 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/76226.