NUMERICAL SIMULATION AND EXPERIMENTAL ANALYSIS OF INERTIAL CELL FOCUSING IN A CONTRACTION-EXPANSION ARRAY (CEA) MICROCHANNEL

2020-10-04
We investigated the cell focusing performance of a CEA type microchannel, which comprises several throttles connecting circular wells in a zigzag arrangement. By obtaining the spatial distribution of the lift force using direct numerical simulations (DNS), we revealed the expected particle trajectories for CEA microchannel by sampling the circular wells with rectangular sections (AR = 1, 2, and 4). Both simulations and initial experiments suggested an improvement in focusing behavior in CEA type microchannel thanks to secondary drag force, arising from the agitation of fluid flow around the channel center.
Citation Formats
A. C. Atik, E. Yıldırım, and H. Külah, “NUMERICAL SIMULATION AND EXPERIMENTAL ANALYSIS OF INERTIAL CELL FOCUSING IN A CONTRACTION-EXPANSION ARRAY (CEA) MICROCHANNEL,” presented at the 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 4 - 09 Ekim 2020, 2020, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/86151.