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Development of an Amperometric Biosensor Based on A Novel Conducting Copolymer for Detection of Anti Dementia Drugs
Date
2015-06-14
Author
Turan, Janset
Kesik, Melis
Söylemez, Saniye
Göker, Seza
Kolb, Marit
Bahadır, Müfit
Toppare, Levent Kamil
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https://hdl.handle.net/11511/88136
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Development of an amperometric biosensor based on a novel conducting copolymer for detection of anti-dementia drugs
Turan, Janset; Kesik, Melis; Soylemez, Saniye; GÖKER, SEZA; Kolb, Marit; Bahadir, Mufit; Toppare, Levent Kamil (2014-12-01)
In this study, a new amperometric biosensor was developed for the detection of the anti-dementia drugs fortified with tap water. For this purpose, electrocopolymerization of 5,6-bis(octyloxy)-4,7-di(thiophen2-yl)benzo[c][1,2,5]oxadiazole(BODT) with (2-(((9H-fluoren-9-yl)methoxy)carbonylamino) acetic acid (FMOC) on graphite electrode was successfully achieved and used as an immobilization matrix. Acetylcholinesterase (AChE) and choline oxidase (ChO) enzyme couple was immobilized on copolymer coated graphite ...
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Development of an oligonucleotide based sandwich array platform for the detection of transgenic elements from plant sources using labal-free PCR products
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Advances in DNA micro and macroarray technologies made these high-throughput systems good candidates for the development of cheaper, faster and easier qualitative and quantitative detection methods. In this study, a simple and cost effective sandwich hybridization-based method has been developed for the rapid and sensitive detection of various unmodified recombinant elements in transgenic plants. Attention was first focused on the optimization of conditions such as time, concentration and temperature using ...
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Laccase (E.C.1.10.3.2, p-benzenediol: oxygen oxidoreductase) catalyzes the oxidation of various aromatic compounds, particularly phenols, which are organic pollutants, present in wastewater. With this specific function this enzyme has had a great impact on the development of biosensors for both environmentally important pollutants and clinically relevant metabolites. There are different detection procedures such as chromatographic and spectrophotometric methods to detect the presence of phenolic compounds i...
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Saatçi, Ebru; İşcan, Mesude; Department of Biochemistry (2005)
In the recent years, environmental pollution becomes a health threatening issue for human beings. Technological developments introduce industrial wastes and heavy metals, and developments in agriculture introduce pesticides into the world that we live. All these toxic wastes accumulate in drinking water and food consumed by humans. Therefore, detection of toxic wastes in all kinds of environmental samples, and development of new detection techniques become an important issue. In this study, development of a...
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J. Turan et al., “Development of an Amperometric Biosensor Based on A Novel Conducting Copolymer for Detection of Anti Dementia Drugs,” 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/88136.