Department of Biology, Thesis

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Thesis (700)

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Yes (638)
No (62)

Author
Afkhami, Pervaneh (2)
Akkaş, Sara Banu (2)
Aktaş, Caner (2)
Ambarlı, Hüseyin (2)
Arıca, Mehmet Yakup (2)

Subject
Biology. (49)
Genetics. (31)
Breast (16)
Natural Sciences (16)
Gene expression. (15)

Date Issued
1980 - 1989 (53)
1990 - 1999 (151)
2000 - 2009 (187)
2010 - 2019 (269)
2020 - 2021 (29)

Recent Submissions

Generation and Characterization of Induced Pluripotent Stem Cell Lines From Multiple Sclerosis Patients and Healthy Individuals
Begentaş, Onur Can; Kiriş, Erkan; Department of Molecular Biology and Genetics (2021-9-8)
Multiple Sclerosis (MS) is an autoimmune disease characterized by inflammation, demyelination, and axonal damage resulting in neurodegeneration in the central nervous system (CNS). Relapsing-remitting MS (RRMS) is the most...
INVESTIGATION OF EFFECTS OF VITAMIN D AND VITAMIN D METABOLIZING CYP450 ISOZYMES ON MULTIPLE SCLEROSIS PATHOPHYSIOLOGY IN ANIMAL MODEL BY MOLECULAR APPROACHES
Evin, Emre; Adalı, Orhan; Department of Biology (2021-8)
Multiple sclerosis (MS) is a complicated, recurrent, and often progressive inflammatory demyelinating autoimmune disease of the central nervous system, yet etiopathogenesis remains unsolved. MS frequency increases with inc...
A PROBABILISTIC ASSESSMENT OF SARS-COV-2 HOST INTERACTIONS IN THE CONTEXT OF META-COMMUNITY AND URBAN ECOLOGY
Nehri, Leman Nur; Eroğlu, Seçkin; Department of Biology (2021-6-29)
Coronavirus disease 2019 (COVID-19) is an ongoing pandemic that was detected in Wuhan, China, in December 2019 and spread all around the world. COVID-19 is caused by Severe acute respiratory syndrome coronavirus 2 (SARS-Co...
ANALYSIS OF TRANSCRIPTOME DATA FOR THE EVALUATION OF METABOLIC DEREGULATION IN CANCER
Sheraj, Ilir; Banerjee, Sreeparna; Department of Biology (2021-6-28)
The great potential of cancer metabolism in tumor development as well as treatment has been appreciated in recent years. In this study, an extensive list of enzymes relevant to central cellular metabolism and metabolite tr...
Selecting 2-FY RNA Aptamers Against SARS-CoV-2 Particle
Öztürk, Meriç; Gözen, Ayşe Gül; İlgü, Müslüm; Department of Molecular Biology and Genetics (2021-6-22)
Corona Virus Disease – 19 (COVID-19) is caused by infection of SARS-CoV-2 from other humans and animals, which results in clinical symptoms like fever, cough, breathing difficulties headache, muscle pain, and diarrhea. Fur...
Small molecule ubiquitin-proteasome system inhibitor library screen reveals botulinum neurotoxin type a inhibitors
Şen, Edanur; Kiriş, Erkan; Department of Biology (2021-2-15)
Botulinum neurotoxins (BoNTs), known as the most potent bacterial toxins, cause potentially lethal disease botulism. BoNTs are classified as category A bioterror agents by many countries because they are easy to produce an...
Genetic diversity differences between parental and progeny population of populus euphratica populations in a fragmented river ecosystem
Çelik, Mert; Kaya, Zeki; Department of Biology (2021-2-15)
Euphrates poplar, also known as desert poplar in the literature, grows along riverbanks in arid and semi-arid regions and is well-known for its high tolerance to broad temperature changes, drought, and soils with high salt...
Evaluation of functional changes in akr1b1 and akr1b10 overexpressing colorectal cancer cell lines
Güderer, İsmail; Banerjee, Sreeparna; Department of Biology (2021-2-15)
Aldo-keto reductases (AKRs) are nicotinamide adenine dinucleotide phosphate (NADPH)-dependent enzymes with diverse cellular metabolism functions. AKR1B1 and AKR1B10 are two of the most studied enzymes in the AKR family. AK...
Comparative transcriptomics of bacillus subtilisbacilysin-negative genotype with particular reference to bacilysin formation
Kocabay, Naz; Özcengiz, Gülay; Department of Molecular Biology and Genetics (2021-2-15)
The Gram-positive model prokaryote Bacillus subtilisis a non-pathogenic organism that is known for producing a wide variety of secondary metabolites with pharmacological andantimicrobial activities.The smalle...
The effect of plant diversity and ground cover onseedling establishment of diplotaxis tenuifolia(l.) dc. in the central anatolian steppe
Kaplan, Ekin; Bilgin, Cemal Can; Tavşanoğlu, Çağatay; Department of Biology (2021-2-15)
Invasive exotic plants increasingly pose a threat to native biodiversity in many parts ofthe world. However, they have rarely become successful in Turkey. One hypothesissuggests a highly diverse native flora avoids estab...
Optimization of a translating ribosomal affinity purification method
Gürcüoğlu, Irmak; Erson Bensan, Ayşe Elif; Department of Biology (2021-2-10)
Novel technologies revealed an immense transcriptome complexity in normal and in cancer cells. One of the reasons for this complexity is isoform variability in cancer cells. Transcript isoforms can arise due to alternative...
Convergent evolution of primate testis transcriptomes in response to mating strategy differences
Yapar, Etka; Somel, Mehmet; Department of Biology (2021-2-01)
In independent mammalian lineages where females mate with multiple males (multimale mating strategies), males have evolved larger testicles relative to those lineages where females mate with fewer males (single-male mating...
Identification of protein partners of setd3 in mouse embryonic stem cells
Güven, Gözde; Terzi Çizmecioğlu, Nihal; Department of Molecular Biology and Genetics (2021-1-26)
Embryonic development is a highly coordinated process that contains rapid cell divisions. During this time, the cells also start differentiation, and at the end of development, the cells become fully differentiated. This d...
The regulation of the CXXC5 gene expression
Yaşar, Pelin; Muyan, Mesut; Department of Molecular Biology and Genetics (2021-1-19)
17β-estradiol (E2) is the main circulating estrogen hormone in the body and is involved in the physiological and pathophysiological regulation of various tissue notably mammary tissue functions. E2 is responsible for cellu...
Genetic diversity pattern in female and male trees of populus euphratica populations sampled from Göksu river basin
Nebioğlu, Nehir; Kaya, Zeki; Department of Biology (2021-1-3)
Populus euphratica, one of the four Populusspecies naturally distributed in Southern and Southeastern Turkey, can survive under extreme conditions like high temperatures, low moisture, salty and calciferous soils. P. euphr...
Investigating the potential of bacillus calmette-guerin vaccine russia strain, cpg oligonucleotides and intravenous immunoglobulin to induce trained immunity in the context of antiviral immunity
Baydemir, İlayda; Gürsel, Mayda; Department of Molecular Biology and Genetics (2020-10-12)
Innate immune cells undergo metabolic and epigenetic reprogramming in response to specific stimuli, that enable a more robust immune response to secondary exposure to a wide variety of pathogens. This process of innate imm...
marT as a global regulatory gene for biofilm formation in Salmonella Typhimurium
Eran, Zeynep; Özcengiz, Gülay; Department of Biology (2020-9)
In this study 14 different genes (fimA, fimD, fimF, fimH, stjB, stjC, csgA, csgD, ompC, sthB, sthE, rmbA, fliZ ve yaiC) thought to be related to marT gene at Salmonella enterica serotype Typhimurium 14028 and each involved...
Behavioral and molecular impact of a stress factor, acaricide perizin on honey bees (apis mellifera) of Turkey
Arslan, Okan Can; Adalı, Orhan; Department of Biology (2020-9)
The effects of acaricide Perizin (coumaphos as the active ingredient) which is used against parasitic mite, Varroa destructor, on three native honey bee subspecies; Apis mellifera caucasica, A. m. carnica and A. m. syria...
Development of an experimental recombinant vaccine formulation composed of LKTA from Mannheimia Haemolytica A1 and P31 and LPPB from Histophilus Somni 8025 against Hovine Respiratory Disease
Türkmen, Nazlı Hilal; Özcengiz, Gülay; Department of Molecular Biology and Genetics (2020-9)
Two major bacterial pathogens of Bovine Respiratory Disease (BRD), Mannheimia haemolytica and Histophilus somni are Gram-negative, opportunistic bacteria that live in upper respiratory tracts of ruminants commensally. The ...
Phenotypic rescue of a Bacilysin-silenced strain of Bacillus Subtilis with Bacilysin supplementation
Ertekin, Ozan; Özcengiz, Gülay; Department of Molecular Biology and Genetics (2020-9)
Bacillus subtilis, the model organism for the gram positive bacteria, is distinguished for its secondary metabolite synthesis. Remarkably, most of these metabolites are small peptides which are generally synthesized non-ri...
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