Bioinks-materials used in printing cells in designed 3D forms

2021-02-01
Tamay, Dilara Goksu
Hasırcı, Nesrin
Use of materials to activate non-functional or damaged organs and tissues goes back to early ages. The first materials used for this purpose were metals, and in time, novel materials such as ceramics, polymers and composites were introduced to the field to serve in medical applications. In the last decade, the advances in material sciences, cell biology, technology and engineering made 3D printing of living tissues or organ models in the designed structure and geometry possible by using cells alone or together with hydrogels through additive manufacturing. This review aims to give a brief information about the chemical structures and properties of bioink materials and their applications in the production of 3D tissue constructs.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Suggestions

Development of clinoptilolite/poly ε-caprolactone -polyethylene glycol - poly ε-caprolactone triblock copolymer based scaffolds for bone tissue engineering
Pazarçeviren, Ahmet Engin; Tezcaner, Ayşen; Keskin, Dilek; Department of Engineering Sciences (2016)
Bone tissue engineering mainly depends on the feasible substitutes with ability to regenerate damaged bone tissue. One of the applications in which bone tissue engineering mainly focuses on is the production of bone tissue scaffolds. These scaffolds are expected to be biocompatible, highly interconnective and porous to provide a niche for colonizing bone cells. In addition, bone tissue scaffolds should be mechanically strong enough to accommodate compression. Scaffolds should also be biodegradable to encour...
Biological Responses of Ceramic Bone Spacers Produced by Green Processing of Additively Manufactured Thin Meshes
Minguella-Canela, Joaquim; Calero, Jose Antonio; Korkusuz, Feza; Korkusuz, Petek; Kankılıç, Berna; Bilgiç, Elif; De los Santos-López, M. Antonia (MDPI AG, 2020-5-30)
Bone spacers are exclusively used for replacing the tissue after trauma and/or diseases. Ceramic materials bring positive opportunities to enhance greater osteointegration and performance of implants, yet processing of porous geometries can be challenging. Additive Manufacturing (AM) opens opportunities to grade porosity levels in a part; however, its productivity may be low due to its batch processing approach. The paper studies the biological responses yielded by hydroxyapatite with beta -TCP (tricalcium ...
Metabolomics analysis of iPSCs derived organoids
Sarı , Vedat; Koçak , Gamze; Reçber, Tuba; Karakülah , Gökhan; Utine , Canan Aslı; Nemutlu , Emirhan; Güven, Sinan (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10)
Regenerative medicine is focused on functional restoration of a particular tissue and organs. Stem cell based miniaturized heterogenous cellular clusters named organoids, exhibit features of organ functionality, self-organization, multicellularity, and utility. Induced pluripotent stem cells (iPSCs), have great potential to develop organoids of specific tissues and utilized in regenerative medicine. Organoid technologies have revolutionized the approach to human development and diseases, providing outstandi...
Biodegradable hydroxyapatite - Polymer composites
Durucan, Caner (2001-04-01)
The fracture of bone due to trauma or due to natural aging is one of the most frequent types of tissue failures. Treatment frequently requires the implantation of ct temporary or permanent prosthesis. The implanted materials may include the components of artificial joints, plates, and screws for fracture fixation. Typically, such implants are intended only to provide structural support or to serve as templates for bone re-growth. In general they are intended to remain in place for the life of the patient or...
Lanthanum doped dicalcium phosphate bone cements for potential use as filler for bone defects
Motameni, Ali; Alshemary, Ammar Z.; Dalgıç, Ali Deniz; Keskin, Dilek; Evis, Zafer (2021-03-01)
The bone defects arising as a result of trauma should be filled to provide a framework to support and encourage the growth of new and living bone tissues. Among the many synthetic bone graft substitutes, self-hardening calcium phosphate (CP) cements have been widely used to repair hard tissue defects. In this study, pure dical-cium phosphate (DCP) and lanthanum (La) modified dicalcium phosphate (La-DCP) bone cements were prepared based on acid/base reaction between beta-tricalcium phosphate (beta TCP) (or L...
Citation Formats
D. G. Tamay and N. Hasırcı, “Bioinks-materials used in printing cells in designed 3D forms,” JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, pp. 0–0, 2021, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/90034.