Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity.

Sen, Edanur
Kota, Krishna P
Panchal, Rekha G
Bavari, Sina
Kiriş, Erkan


Screening and characterization of catalytic composite membranes for ethyllactate production
Oğuzer, Özge; Karakaş, Gürkan; Department of Chemical Engineering (2004)
In this research, molybdophosphoric acid (PMo) was blended with polysulfone polymer (PSF) and form a film catalyst by using a common solvent dimethylformamide (DMF). Kinetic and mass transfer parameters were evaluated for catalytic films in ethanol lactic acid esterification reaction as film surface area, film thickness and catalyst loading were varied at 50?C, 1 atm and 1:1 ethyl alcohol to lactic acid mole ratio conditions. Also prepared films were characterized by DSC, TGA, FTIR, X-ray and SEM analysis. ...
Screening of Corchorus olitorius L. extracts for antioxidant and antibacterial activities
Iseri, Ozlem Darcansoy; Korpe, Didem Aksoy; ŞAHİN, FERİDE İFFET; Cabi, Evren; Haberal, Mehmet (2011-09-01)
Analysis and characterization of the pichia pastoris secretome for pharmaceutical protein production
Kırlı, Hatice Pınar; Koku, Harun; Department of Chemical Engineering (2019)
Human growth hormone (hGH) is used for the treatment of many diseases like short stature in children. It is generally purified by using affinity chromatography. Due to the high cost of affinity chromatography, other chromatographic techniques have been investigated for purification of recombinant human growth hormone (rhGH). The aim of this work was to explore chromatographic purification protocols for rhGH from the secretome of Pichia pastoris. First, the entire secretome was examined by 2-D gel electropho...
Investigating of oral constraceptives effects on weight gaining mechanisms in polycystic ovary sendrome (PCOS) patients
Yanık, Tülin; Yildiz, Bulent Okan (2010-08-01)
Investigation of schizophrenia related genes and pathways through genome wide association studies
Döm, Hüseyin Alper; Aydın Son, Yeşim; Department of Bioinformatics (2013)
Schizophrenia is a complex mental disorder that is commonly characterized as deterioration of intellectual process and emotional responses and affects 1% of any given population. SNPs are single nucleotide changes that take place in DNA sequences and establish the major percentage of genomic variations. In this study, our goal was to identify SNPs as genomic markers that are related with schizophrenia and investigate the genes and pathways that are identified through the analysis of SNPs. Genome wide associ...
Citation Formats
E. Sen, K. P. Kota, R. G. Panchal, S. Bavari, and E. Kiriş, “Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity.,” Frontiers in pharmacology, vol. 12, pp. 763950–763950, 2021, Accessed: 00, 2021. [Online]. Available: