Design of a contact type acoustic sensor for the noninvasive diagnosis of cardiovascular obstructions

Download
2022-12
Balçık, Çağlar Yazgan
The idea of determining arterial occlusions by non-invasive methods is a subject that has been studied for many years. Current diagnostic methods are mostly invasive, potentially risky and costly. There are studies in the literature that concentrate on the turbulent flow occurring in the arteries as a result of arterial occlusions. This results in acoustic pressure exciting the internal artery wall. In this study, a contact-type acoustic sensor design was carried out with based on the existing studies in the literature and a prototype was produced. The contact-type acoustic sensor that has been designed and prototyped has a receiving sensitivity of –126 dBV (ref 1 Pa) and a 5-dB beamwidth of 70 degrees. In addition, the prototype produced is a structure that can be used as a contact-type acoustic sensor with a fixed response up to 2000 Hz. In addition, an experimental setup modeling arterial occlusion was produced to validate the design. Measurements were made with the prototype sensor at occlusion rates of 99%, 90% and 70%, at blood flow rates of 10 mL/sn and 20 mL/sn. The results have been found to be relevant to the findings available in the past studies. The effect of turbulent flow in the arteries has been found to be between 100 Hz and 600 Hz and dominant around 300 Hz. The threshold to detect the occlusion in the artery by using acoustic methods has been determined to be 70% which is in agreement with the existing literature.

Suggestions

Use of Activation Time Based Kalman Filtering in Inverse Problem of Electrocardiography
Aydin, Umit; Serinağaoğlu Doğrusöz, Yeşim (2008-11-27)
The goal of this study is to solve inverse problem of electrocardiography (ECG) in terms of epicardial potentials using body surface (torso) potential measurements. The problem is ill-posed and regularization must be applied. Kalman filter is one of the regularization approaches, which includes both spatial and temporal correlations of epicardial potentials. However, in order to use the Kalman filter, one needs the state transition matrix (STM) that models the time evolution of the epicardial potentials. In...
Application of 2D Digital Image Correlation Three Point Flexure Test of Reinforced Concrete Beam
Albostan, Utku; Kurç, Özgür (null; 2016-09-21)
Digital image correlation (DIC) method has been used in many disciplines to measure displacement and strain without any contact to the specimen. Moreover, it is usually a cheaper method when compared with other measurement techniques. In this technique, a single or stereo digital cameras are needed for the 2D and 3D measurements, respectively. Images used for correlation are generally acquired from videos shot by high speed cameras. Accordingly, their resolutions and measurement accuracies are not sufficien...
Investigation of Multi-task Deep Neural Networks in Automated Protein Function Prediction
Rifaioğlu, Ahmet Süreyya; Martin, Maria Jesus; Atalay, Rengül; Atalay, Mehmet Volkan; Doğan, Tunca (2017-07-20)
Functional annotation of proteins is a crucial research field for understanding molecular mechanisms of living-beings and for biomedical purposes (e.g. identification of disease-causing functional changes in genes and for discovering novel drugs). Several Gene Ontology (GO) based protein function prediction methods have been proposed in the last decade to annotate proteins. However, considering the prediction performances of the proposed methods, it can be stated that there is still room for significant imp...
Estimation of fracture relative permeabilities from unsteady state corefloods
Akın, Serhat (2001-06-01)
A methodology to test the possible deviations of fracture relative permeabilities from straight-line relationship with saturation is discussed. It is shown that with matrix relative permeability data known, it is possible to obtain fracture relative permeabilities by history matching experimental data with double porosity numerical models output. Rather than linear saturation dependence, fracture relative permeability is a power law function of the corresponding phase saturation. The impact of several impor...
A new outlier detection method based on convex optimization: application to diagnosis of Parkinson's disease
TAYLAN, PAKİZE; Yerlikaya-Ozkurt, Fatma; Bilgic Ucak, Burcu; Weber, Gerhard Wilhelm (Informa UK Limited, 2020-12-01)
Neuroscience is a combination of different scientific disciplines which investigate the nervous system for understanding of the biological basis. Recently, applications to the diagnosis of neurodegenerative diseases like Parkinson's disease have become very promising by considering different statistical regression models. However, well-known statistical regression models may give misleading results for the diagnosis of the neurodegenerative diseases when experimental data contain outlier observations that l...
Citation Formats
Ç. Y. Balçık, “Design of a contact type acoustic sensor for the noninvasive diagnosis of cardiovascular obstructions,” M.S. - Master of Science, Middle East Technical University, 2022.