A Novel enantioselective synthesis of NMDA agonist 2-(Carboxycyclopropyl) glycine

Download
068607.pdf
1997
Çağır, Ali
Show full item record
72
views
0
downloads
https://hdl.handle.net/11511/1197
Graduate School of Natural and Applied Sciences, Thesis

Suggestions

A novel asymmetric synthesis of highly enantiomerically enriched norbornane-type diamine derivatives
BOLM, CARSTEN; SCHİFFERS, INGO; ATODİRESEİ, IULİANA; Özçubukçu, Salih; RAABE, GERHARD (Royal Society of Chemistry (RSC), 2003-01-01)
The simple and highly enantioselective methanolysis of norbornene dicarboxylic acid anhydride mediated by quinidine leads to the corresponding cis-monomethyl ester with 98% ee. By means of selective ester epimerization, followed by Curtius degradation of the intermediate trans-diacyl azide, two optically active norbornane-type diamines are obtained as their hydrochloric salts. Liberating the amine with an excess of triethylamine in situ and subsequent derivatization affords potential C-1-symmetric ligands f...
A novel synthesis of 1,2,4-oxadiazoles and isoxazoles
KIVRAK, Arif; Zora, Metin (Elsevier BV, 2014-01-28)
A novel synthesis of 1,2,4-oxadiazoles and isoxazoles is described by utilizing the reactions between amidoximes and alpha,beta-alkynic aldehydes and/or ketones. Conjugate addition products, obtained from amidoximes and alpha,beta-alkynic aldehydes and/or ketones, afford 1,2,4-oxadiazoles and isoxazoles when treated with bases and acids, respectively. 1,2,4-Oxadiazoles can also be synthesized directly from amidoximes and alpha,beta-alkynic aldehydes in a one-pot manner under basic conditions. The reactions ...
A novel enantioselective synthesis of furyl aziridine as a-amino acid precursor
Aydoğan, Kenan; Demir, Ayhan S.; Department of Chemistry (1993)
A novel synthesis of unsaturated nitriles via epichlorohydrins intermediates
Güzen Kandemir, Canan; Tanyeli, Cihangir; Department of Chemistry (1994)
A novel enantioselective synthesis of o-Thienyl alkyl amines
ibrahimzade, Nezire; Demir, Ayhan S.; Department of Chemistry (1992)
Citation Formats
A. Çağır, “A Novel enantioselective synthesis of NMDA agonist 2-(Carboxycyclopropyl) glycine,” Middle East Technical University, 1997.
METU IIS - Integrated Information Service open@metu.edu.tr