Phytoestrogen contents of selected foods

Download

index.pdf

Date

2004

Author

Gültekin, Esra

Metadata

Show full item record

Item Usage Stats

207
views

155
downloads

Phytoestrogens are naturally occurring chemicals of plant origin that have the ability to cause estrogenic and/or anti-estrogenic effects due to their structural similarities to the human hormone oestradiol. It has been proposed that phytoestrogens protect against a wide range of ailments, including breast and prostate cancers, cardiovascular disease, osteoporosis, and menopausal symptoms. Daidzein, biochanin A and especially genistein which has been reported to be the most biologically active dietary phytoestrogen attract great deal of interest in today̕s researches. In this study, twenty different food items, including legumes, fruits, nuts and herbs, (haricot beans, chickpeas, green lentils, red lentils, soybeans, licorice root, yarrow, dried chestnuts, prunes, raisins, currants, black cumin, dried apricots, dried parsley, dried dates, dried figs, sage (from Aegean region), sage (from Mediterranean region), grapevine leaves, gilaburu) were selected. Following an extraction procedure employing acid hydrolysis and heating; they were analysed for their daidzein, genistein and biochanin A contents using a reversed-phase C18 column with linear gradient elution on a high-performance liquid chromatography (HPLC) coupled with diode-array detector (DAD). Soybeans were found to contain high amounts of daidzein (91.36 mg/100 g) and genistein (85.57 mg/100 g). Chickpeas were found to contain much less amount of genistein (0.89 mg/100 g) compared with that of soybeans and also biochanin A (0.95 mg/100 g) which was not detected in soybeans. None of daidzein, genistein and biochanin A was detected in the remaining eighteen food items.

Subject Keywords

Photochemistry.

URI

http://etd.lib.metu.edu.tr/upload/12605398/index.pdf
https://hdl.handle.net/11511/14411

Collections

Graduate School of Natural and Applied Sciences, Thesis

Suggestions

OpenMETU
Core

DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles Hoffmann, Thomas; Marıon, Antoıne; Antes, Iris (Springer Science and Business Media LLC, 2017-02-02) Background: T cell receptor (TCR) molecules are involved in the adaptive immune response as they distinguish between self- and foreign-peptides, presented in major histocompatibility complex molecules (pMHC). Former studies showed that the association angles of the TCR variable domains (Va/V beta) can differ significantly and change upon binding to the pMHC complex. These changes can be described as a rotation of the domains around a general Center of Rotation, characterized by the interaction of two highly...
Biodegradation of the Allelopathic Chemical Pterostilbene by a Sphingobium sp. Strain from the Peanut Rhizosphere Yu, Ri-Qing; Kurt, Zöhre; He, Fei; Spain, Jim C. (American Society for Microbiology, 2019-03-01) Many plants produce allelopathic chemicals, such as stilbenes, to inhibit pathogenic fungi. The degradation of allelopathic compounds by bacteria associated with the plants would limit their effectiveness, but little is known about the extent of biodegradation or the bacteria involved. Screening of tissues and rhizosphere of peanut (Arachis hypogaea) plants revealed substantial enrichment of bacteria able to grow on resveratrol and pterostilbene, the most common stilbenes produced by the plants. Investigati...
Bioactive thiazole and benzothiazole derivatives Rouf, Abdul; Tanyeli, Cihangir (2015-06-05) The heterocycles are the versatile compounds existing in almost all natural products and synthetic organic compounds, usually associated with one or the other biological activity. Among the heterocycles the thiazoles and benzothiazoles occupy a prominent position. They possess a broad range of biological activities and are found in many potent biologically active molecules and drugs such as vitamin thiamine, sulfathiazol (antimicrobial drug), ritonavir (antiretroviral drug), abafungin (antifungal drug) and ...
Improved solubility of celecoxib by inclusion in SBA-15 mesoporous silica: Drug loading in different solvents and release Eren, Zeynep Seda; Tuncer, Sinem; Gezer, Gamze; Yildirim, Leyla Tatar; Banerjee, Sreeparna; Yılmaz, Ayşen (2016-11-15) In this study, celecoxib (CLX), a highly hydrophobic nonsteroidal anti-inflammatory drug with relatively low bioavailability, was used as a model drug to determine loading in different solvents and release properties from silica particles. Hydrothermal synthesis method was used to synthesize SBA-15 particles, which were functionalized by post-synthesis grafting method with (3-Aminopropyl) triethoxysilane (APTES). Additionally, boron doped SBA-15 samples were prepared to generate borosilicate samples. After ...
Biodegradation of Chlorobenzene, 1,2-Dichlorobenzene, and 1,4-Dichlorobenzene in the Vadose Zone Kurt, Zöhre (2013-07-02) Much of the microbial activity in nature takes place at interfaces, which are often associated with redox discontinuities. One example is the oxic/anoxic interface where polluted groundwater interacts with the overlying vadose zone. We tested whether microbes in the vadose zone can use synthetic chemicals as electron donors and thus protect the overlying air and buildings from groundwater pollutants. Samples from the vadose zone of a site contaminated with chlorobenzene (CB), 1,2-dichlorobenzene (12DCB), an...

Citation Formats

E. Gültekin, “Phytoestrogen contents of selected foods,” M.S. - Master of Science, Middle East Technical University, 2004.