Investigation of the effects of different macrostructures on conjugated polymer based amperometric biosensor performance

Büber, Ece
In this thesis, the use of different macrostructures in the surface design of conjugated polymer based amperometric biosensors was investigated since surface properties play a crucial role in the performance of biosensors. Conjugated polymers (CPs) provide biosensors superior features since they exhibit conductivity, high mechanical strength and processability. Moreover, phthalocyanines (Pcs) are promising molecules for biosensor applications due to their electronic properties, rich redox chemistry and high electrochemical stability. In addition to phthalocyanines, dendrimers are suitable host molecules for accommodation of guest molecules due to their three-dimensional structure having an internal void space. Especially, poly(amidoamine) (PAMAM), can be used in biosensor applications since it contains a number of terminal amino groups which enhances the attachment of biomolecules. Multi-walled carbon nanotubes (MWCNTs) have also extensively used in biosensor applications since they are compatible with biomolecules in addition to their mechanical strength, stability and conductivity properties. By taking the advantages of these materials, two novel glucose biosensors; CPs/MWCNTs/ZnPc and CPs/MWCNTs/PAMAM were fabricated. Their operational and kinetic parameters and surface features were characterized and the biosensors were successfully tested for real time analyses.


Design of Carbon Nanotube Modified Conducting Polymer for Biosensing Applications
Ozdemir, Caglar; Tuncagil, Sevinc; ODACI DEMİRKOL, DİLEK; TİMUR, SUNA; Toppare, Levent Kamil (2011-01-01)
An electrochemical biosensor with improved performance was designed through the immobilization of glucose oxidase (GOx) onto conducting polymer of 4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine (SNS-NH2) modified with carbon nanotubes (CNTs). For the optimization and characterization of the biosensor, pH profile, enzyme loading, reproducibility, operational stability experiments were carried out. It was found that the use of CNTs in a biosensing system enhanced the biosensor response. The linear relati...
Study of the structural and optical properties of thallium gallium disulfide (TlGaS2) thin films grown via thermal evaporation
Isik, M.; KARATAY, AHMET; Ech-Chergui, A.N.; Hasanlı, Nızamı (2022-07-01)
© 2022 IOP Publishing Ltd.Thallium gallium disulfide (TlGaS2) belonging to layered structured semiconducting family has been a significant compound due to its outstanding characteristics. Its layered characteristics take attention for two-dimensional (2D) material research area and thus TlGaS2 is known as promising layered compound to develop 2D materials for optoelectronic devices. To the best of our knowledge, the present work is the first one investigating TlGaS2 thin films grown by thermal evaporation m...
Spectrophotometric and amperometric biosensors based on conducting polymers of 1-Benzyl-2,5-DI(Thiophen-2-YL)-1H-Pyrrole and (4,7-Dithien-2-YL-2,1,3-Benzothiadiazole)
Tanrıverdi, Simla; Toppare, Levent Kamil; Timur, Suna; Department of Polymer Science and Technology (2012)
In this thesis, two different biosensors based on conducting polymers of (4,7-dithien-2-yl-2,1,3-benzothiadiazole) (TBTD) and 1-benzyl-2,5 di(thiophene-2-yl)-1H-Pyrrole (SNBS) were prepared. Electrochemical technique was used for polymerization of conducting polymers and two different immobilization techniques were used for immobilizing enzyme into the conducting polymer matrices. The proposed biosensors were characterized and optimized. Optimum pH, thickness, enzyme amount were determined and linearity, re...
Investigation of thermal degradation characteristics of polyamide-6 containing melamine or melamine cyanurate via direct pyrolysis mass spectrometry
Isbasar, Ceyda; Hacaloğlu, Jale (2012-01-01)
In this work the changes in thermal degradation characteristics of polyamide 6 (PA6) in the presence of melamine (Me) or melamine cyanurate (MC) were investigated systematically via direct pyrolysis mass spectrometry. Though thermal stability of PA6 was not affected by the presence of flame retardants, the changes in the products and in their distributions were detected. The reaction of carbonyl groups of PA6 with amine groups of melamine was the main cause for the changes in the product distribution. In th...
Investigation of the effect of heteroatom and integration of boron on benzodithiophene and pyrazine containing conjugated polymers for photovoltaic applications
Abacıoğlu, Yeşim; Çırpan, Ali; Sürdem, Sedat; Department of Chemistry (2021-7)
In the context of this thesis, two different subjects were investigated for photovoltaic applications of conjugated polymers; the effect of heteroatom and integration of boron. The element boron has received considerable attention in the research of alternative energy sources due to its superior properties, and incorporation of boron in conjugated systems is considered as an important strategy to achieve efficient photovoltaics. In this sense, benzodithiophene and pyrazine containing conjugated polymer was...
Citation Formats
E. Büber, “Investigation of the effects of different macrostructures on conjugated polymer based amperometric biosensor performance,” M.S. - Master of Science, Middle East Technical University, 2018.