Dilek Keskin

E-mail

dkeskin@metu.edu.tr

Department

Department of Engineering Sciences

ORCID

0000-0001-7824-488X

Scopus Author ID

36967297400

Web of Science Researcher ID

AAZ-6462-2020

Development and characterization of manganese-doped hydroxyapatite-incorporated wet-electrospun polycaprolactone scaffolds Samiei, Alaleh; Jodati, Hossein; Evis, Zafer; Keskin, Dilek (2025-12-12) Bioceramic-incorporated polymer-based scaffolds have gained more interest as a promising and effective approach in bone tissue engineering (BTE) applications. This study is the first to investigate the role of incorporated...
Novel barium-doped-baghdadite incorporated PHBV-PCL composite fibrous scaffolds for bone tissue engineering Sadreddini, Sanaossadat; Jodati, Hossein; Evis, Zafer; Keskin, Dilek (2023-12-01) Bioceramic/polymer composites have dragged a lot of attention for treating hard tissue damage in recent years. In this study, we synthesized barium-doped baghdadite (Ba-BAG), as a novel bioceramic, and later developed fibr...
Diatom silica frustules-doped fibers for controlled release of melatonin for bone regeneration Deniz Dalgic, Ali; Atila, Deniz; Tezcaner, Ayşen; Gürses, Senih; Keskin, Dilek (2023-03-15) Sustained release of a bioactive agent from a tissue engineering scaffold is one of the most common strategies to improve regenerative potential of the construct. However, depending on the chemistry of the agent, achieving...
Improvement of bioactivity with dual bioceramic incorporation to nanofibrous PCL scaffolds Altunordu, Gercem; Tezcaner, Ayşen; Evis, Zafer; Keskin, Dilek (2023-03-01) Bone tissue injuries, diseases or related clinical interventions require bone tissue engineering (BTE) approaches for regeneration of large bone defects, especially for compromised situations. Most BTE applications in lite...
Functionalization of graphene oxide quantum dots for anticancer drug delivery Mohammed-Ahmed, Heba K.; Nakipoğlu, Mustafa; Tezcaner, Ayşen; Keskin, Dilek; Evis, Zafer (2023-02-01) Graphene quantum dots (GQDs) have a wide range of applications in biomedical applications, particularly anticancer drug delivery. In this study, graphene oxide quantum dots conjugated with glucosamine and boric acid (GOQDs...
Injectable methacrylated gelatin/thiolated pectin hydrogels carrying melatonin/tideglusib-loaded core/shell PMMA/silk fibroin electrospun fibers for vital pulp regeneration Atila, Deniz; Keskin, Dilek; Lee, Yuan-Ling; Lin, Feng-Huei; Hasirci, Vasif; Tezcaner, Ayşen (2023-02-01) Use of injectable hydrogels attract attention in the regeneration of dental pulp due to their ability to fill non-uniform voids such as pulp cavities. Here, gelatin methacrylate/thiolated pectin hydrogels (GelMA/PecTH) car...
Alginate/gelatin/boron-doped hydroxyapatite-coated Ti implants: in vitro and in vivo evaluation of osseointegration Pazarçeviren, Ahmet Engin; Evis, Zafer; Dikmen, Tayfun; Altunbaş, Korhan; Yaprakçı, Mustafa V.; Keskin, Dilek; Tezcaner, Ayşen (2023-01-01) In this study, boron-doped hydroxyapatite (BHT)-loaded alginate/gelatin-based (A/G) hydrogel coating on Ti was fabricated to support bone integration through triggering osteoinduction, vascularization and immunomodulation....
Kemik Tedavisinde Kullanılan Hidrojeller Dalgıç, Ali Deniz; Keskin, Dilek (ODTÜ Yayıncılık, 2023-01-01)
Graphene oxide reinforced doped dicalcium phosphate bone cements for bone tissue regenerations Motameni, Ali; Alshemary, Ammar Z.; Dalgic, Ali Deniz; Keskin, Dilek; Evis, Zafer (2022-09-01) Artificial bone cements have widespread applications in orthopedic and dental surgeries. Nevertheless, there is a need to develop novel materials for artificial bone cements due to limitations like short-service life, weak...
Seamless and robust alginate/gelatin coating on Ti-6Al-4V as a gap filling interphase Pazarçeviren, Ahmet Engin; Akbaba, Sema; Tezcaner, Ayşen; Keskin, Dilek; Evis, Zafer (2022-04-01) Durable, biocompatible and interphases composed of interpenetrating network of alginate and gelatin (A/G) with long shelf-life were produced. Titanium implants were conditioned with acid:peroxide followed by sodium hydroxi...

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