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pH-Responsive Nano Carriers for Doxorubicin Delivery

2015-04-01
Bagherifam, Shahla
Skjeldal, Frode Miltzow
Griffiths, Gareth
Maelandsmo, Gunhild M.
Engebraten, Olav
Nystrom, Bo
Hasırcı, Vasıf Nejat
Hasırcı, Nesrin
Purpose The aim of this study was to design stimuli-responsive nanocarriers for anti-cancer drug delivery. For this purpose, doxorubicin (DOX)-loaded, polysebacic anhydride (PSA) based nanocapsules (NC) were combined with pH-sensitive poly (L-histidine) (PLH).