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The effects of local and sustained release of fibroblast growth factor on wound heating in esophageal anastomoses

2008-02-01
Fedakar-Senyucel, Mine
Bingo-Kologlu, Meltem
Vargun, Rahsan
Akbay, Canan
Sarac, F. Nursen
Renda, Nurten
Hasırcı, Nesrin
Gollu, Gulnur
DİNDAR, HÜSEYİN
Background/ Purpose: Postsurgical complications, such as anastomotic leaks in patients with esophageal atresia, have remained unchanged during the last 3 decades. Growth factors enhance healing in several wound-healing models. Therefore, an experimental study was used to evaluate the effects of local and sustained release of basic fibroblast growth factor (FGF) on wound healing in esophageal anastomoses.