Basic fibroblast growth factor loaded polypropylene meshes in repair of abdominal wall defects in rats

Date

2010-11-01

Author

Heybeli, T.
Kulacoglu, H.
GENÇ, VOLKAN
Ergul, Z.
Ensari, C.
Kızıltay, Aysel
Yilmazer, D.
Serbetci, K.
Hasırcı, Nesrin

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Background and Aim: Incisional hernia following laparotomy and recurrent herniation after its repair are still common problems in spite of mesh augmentation. The underlying biological mechanism may be related to collagen metabolism. Recently, some members of growth factors family have been tested in the prevention of wound failure and incisonal hernia formation. Growth factors may promote fibroblast proliferation and collagen deposition. In the present study, we searched the effects of basic fibroblast growth factor (bFGF) loaded polypropylene meshes in an incisional hernia model in rats.

Subject Keywords

Growth factor, Fibroblast, FGF, Wound healing, Abdominal wall, Incisional hernia, Hernia repair, Mesh

URI

https://hdl.handle.net/11511/55691

Journal

CHIRURGIA

Collections

Test and Measurement Center In advanced Technologies (MERKEZ LABORATUVARI), Article

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Citation Formats

T. Heybeli et al., “Basic fibroblast growth factor loaded polypropylene meshes in repair of abdominal wall defects in rats,” CHIRURGIA, pp. 809–816, 2010, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/55691.