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In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration
Date
2020-12-01
Author
Tombuloğlu, Ayşegül
Çöpoğlu, Hülya
Aydın Son, Yeşim
Güray, Nülüfer Tülün
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Boron is a prominent part of the human diet and one of the essential trace elements for humans. Dietary boron is mostly transformed into boric acid within the body and has been associated with desirable health outcomes. Non-dietary resources of boron, such as boron-based drugs and occupational exposure, might lead to excessive boron levels in the blood and provoke health adversities. The liver might be particularly sensitive to boron intake with ample evidence suggesting a relation between boron and liver function, although the underlying molecular processes remain largely unknown.
Subject Keywords
Boric acid
,
IC50
,
Cytotoxicity
,
DNA damage
,
Microarray
,
HepG2
URI
https://hdl.handle.net/11511/31208
Journal
Journal Of Trace Elements In Medicine And Biology
DOI
https://doi.org/10.1016/j.jtemb.2020.126573
Collections
Graduate School of Informatics, Article
Citation Formats
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BibTeX
A. Tombuloğlu, H. Çöpoğlu, Y. Aydın Son, and N. T. Güray, “In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration,”
Journal Of Trace Elements In Medicine And Biology
, vol. 62, pp. 126–130, 2020, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/31208.