A Monostyryl Boradiazaindacene (BODIPY)-based lanthanide-free colorimetric and fluorogenic probe for sequential sensing of copper (II) ions and dipicolinic acid as a biomarker of bacterial endospores

Date

2019-09-05

Author

Cetinkaya, Yagmur
Yurt, Mediha Nur Zafer
Öktem, Hüseyin Avni
Yilmaz, M. Deniz

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

185
views

0
downloads

A new catechol-substituted monostyryl boradiazaindacene (BODIPY)-based lanthanide-free colorimetric and fluorogenic probe was developed for the sequential detection of Cu2+ ions and dipicolinic acid (DPA), a distinctive biomarker of bacterial endospores, with high sensitivity and selectivity. In the presence of Cu2+ ions, the blue solution of the probe changes to cyan and the fluorescence is quenched, however, the cyan color changes to blue immediately and the fluorescence is restored on contact with DPA, resulting from competitive binding of DPA that interact with Cu2+ ions. A practical application by using Geobacillus stearothermophilus spores was further studied and as low as 1.0 x 10(5) spores were detected.

Subject Keywords

Bacterial endospores, Dipicolinic acid, BODIPY, Copper complex, Ratiometric detection

URI

https://hdl.handle.net/11511/32898

Journal

JOURNAL OF HAZARDOUS MATERIALS

DOI

https://doi.org/10.1016/j.jhazmat.2019.05.108

Collections

Department of Biology, Article

Suggestions

OpenMETU
Core

A triazoloquinoxaline and benzodithiophene bearing low band gap copolymer for electrochromic and organic photovoltaic applications HACIOGLU, Serife O.; UNLU, Naime A.; AKTAS, Ece; HIZALAN, Gonul; Yildiz, Esra D.; Çırpan, Ali; Toppare, Levent Kamil (2017-06-01) A new triazoloquinoxaline and benzodithiophene based copolymer was synthesized to investigate its electro-chemical, optical and photovoltaic behaviors. According to the polymer design, combination of two acceptor units (benzotriazole and quinoxaline) which contribute imine bonds to the structure and a triazoloquinoxaline unit for enhancing electron accepting ability was pursued. As a result of electrochemical studies, the copolymer PTQBDT has a low lying HOMO energy level as - 5.23 eV which increases the ch...
A flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensing BULUT, Umut; Oyku Sayin, Vuslat; Altin, Yasin; Can Cevher, Sevki; Çırpan, Ali; Celik Bedeloglu, Ayse; Soylemez, Saniye (2023-01-01) Herein, a specific and stable biosensor for glucose using a flexible, modified electrode with a carbon nanofiber (CNF) and a novel conjugated polymer including three moieties of benzotriazole, benzodithiophene, and benzenediamine (P-BDT-BTz:BDA) as a platform was designed. For this purpose, polyacrylonitrile (PAN) nanofiber mats were obtained by a solution-based electrospinning method. PAN nanofiber mats were stabilized and carbonized to turn into carbon nanofibers and the sensing platform was formed by com...
A benzimidazole-based turn-off fluorescent sensor for selective detection of mercury (II) ERGÜN, EMİNE GÜL CANSU; Ertaş, Gülay; Eroglu, Deniz (Elsevier BV, 2020-05-01) In this study, potential fluorescent sensing ability of a donor-acceptor-donor type conjugated molecule over various metal ions (Ni(II), Zn(II), Cu(II), Cd(II), Pb(II), Fe(II), Fe(III), As(III), Se(IV), Hg(I) and Hg(II)) was investigated. The sensor basically includes benzimidazole and 3,4-propylenedioxythiophene as the acceptor and donor units, respectively. Solution of the sensor in tetrahydrofuran exhibits an emission with having a maximum at 632 nm. Since having insolubility of some ions in tetrahydrofu...
A thiazolothiazole containing multichromic polymer for glucose detection Soylemez, S.; Kaya, H. Z.; Udum, Y. A.; Toppare, Levent Kamil (Department of Polymer Engineering, Scientific Society of Mechanical Engineering, 2019-10-01) Donor-acceptor (DA) type monomers namely 2,5-di(thiophen-2-yl)thiazolo[5,4-d]thiazole (TTzTh) and 2,5-bis(3-methylthiophen-2-yl)thiazolo[5,4-d]thiazole (TTzMTh) were synthesized and their electrochemical and optoelectronic properties were investigated in detail. The spectro-electrochemical analysis showed that the alkyl chain substitution results in a shift in the onset of the pi-pi* transition towards longer wavelengths. Depending on the donor substituents, the polymers exhibited optical band gaps 1.65 and...
A Novel Amperometric Glutamate Biosensor Based on Glutamate Oxidase Adsorbed on Silicalite Soldatkina, O. V.; Soldatkin, O. O.; Kasap, B. Ozansoy; Kucherenko, D. Yu.; Kucherenko, I. S.; Akata Kurç, Burcu; Dzyadevych, S. V. (2017-04-07) In this work, we developed a new amperometric biosensor for glutamate detection using a typical method of glutamate oxidase (GlOx) immobilization via adsorption on silicalite particles. The disc platinum electrode (d = 0.4 mm) was used as the amperometric sensor. The procedure of biosensor preparation was optimized. The main parameters of modifying amperometric transducers with a silicalite layer were determined along with the procedure of GlOx adsorption on this layer. The biosensors based on GlOx adsorbed...

Citation Formats

Y. Cetinkaya, M. N. Z. Yurt, H. A. Öktem, and M. D. Yilmaz, “A Monostyryl Boradiazaindacene (BODIPY)-based lanthanide-free colorimetric and fluorogenic probe for sequential sensing of copper (II) ions and dipicolinic acid as a biomarker of bacterial endospores,” JOURNAL OF HAZARDOUS MATERIALS, pp. 299–304, 2019, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/32898.