Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
A flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensing
Date
2023-01-01
Author
BULUT, Umut
Oyku Sayin, Vuslat
Altin, Yasin
Can Cevher, Sevki
Çırpan, Ali
Celik Bedeloglu, Ayse
Soylemez, Saniye
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
155
views
0
downloads
Cite This
Herein, a specific and stable biosensor for glucose using a flexible, modified electrode with a carbon nanofiber (CNF) and a novel conjugated polymer including three moieties of benzotriazole, benzodithiophene, and benzenediamine (P-BDT-BTz:BDA) as a platform was designed. For this purpose, polyacrylonitrile (PAN) nanofiber mats were obtained by a solution-based electrospinning method. PAN nanofiber mats were stabilized and carbonized to turn into carbon nanofibers and the sensing platform was formed by combining the nanofibers on a defined area of a flexible polyethylene terephthalate (PET) substrate. In addition, a random conjugated polymer, P-BDT-BTz:BDA, was synthesized, characterized, and used as a modifier of a CNF-coated transducer surface for glucose detection. The effect of each parameter on biosensor response was evaluated. Under optimized conditions, the electrode responded to glucose in a linear concentration range of 20 µM to 500 µM with a detection limit of 8.5 µM. In addition, it was observed that the designed biosensor has a good sensing ability for glucose in beverages. The results of our study show that the proposed amperometric glucose oxidase (GOx)-based biosensor has high specificity, a low limit of detection, and an extended range of linear detection for glucose.
Subject Keywords
Carbon nanofiber
,
Conjugated random polymer
,
Enzyme immobilization
,
Glucose detection
,
Glucose oxidase
URI
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85142124632&origin=inward
https://hdl.handle.net/11511/101692
Journal
Microchemical Journal
DOI
https://doi.org/10.1016/j.microc.2022.108148
Collections
Department of Chemistry, Article
Suggestions
OpenMETU
Core
A novel approach for the fabrication of a flexible glucose biosensor: The combination of vertically aligned CNTs and a conjugated polymer
GOKOGLAN, Tugba Ceren; SOYLEMEZ, Saniye; KESİK, Melis; DOGRU, Itir Bakis; TUREL, Onur; YÜKSEL, Recep; Ünalan, Hüsnü Emrah; Toppare, Levent Kamil (2017-04-01)
A novel flexible glucose biosensor using vertically aligned carbon nanotubes (VACNT) and a conjugated polymer (CP) was fabricated. A scaffold based on VACNT grown on aluminum foil (VACNT-Al foil) with poly (9,9-di-(2-ethylhexyl)-fluorenyl-2,7-diyl)-end capped with 2,5-diphenyl-1,2,4-oxadiazole (PFLO) was used as the immobilization matrix for the glucose biosensor. Glucose oxidase (GOx) was immobilized on a modified indium tin oxide (ITO) coated polyethylene terephthalate (PET) electrode surface. The biosens...
A novel promising biomolecule immobilization matrix: Synthesis of functional benzimidazole containing conducting polymer and its biosensor applications
Uzun, Sema Demirci; Unlu, Naime Akbasoglu; Sendur, Merve; Kanik, Fulya Ekiz; TİMUR, SUNA; Toppare, Levent Kamil (2013-12-01)
In order to construct a robust covalent binding between biomolecule and immobilization platform in biosensor preparation, a novel functional monomer 4-(4,7-di(thiophen-2-yl)-1H-benzo[d]imidazol-2yl)benzaldehyde (BIBA) was designed and successfully synthesized. After electropolymerization of this monomer, electrochemical and spectroelectrochemical properties were investigated in detail. To fabricate the desired biosensor, glucose oxidase (GOx) was immobilized as a model enzyme on the polymer coated graphite ...
Benzodithiophene bearing conjugated polymer-based surface anchoring for sensitive electrochemical glucose detection
BULUT, Umut; SAYIN, Vuslat Öykü; Cevher, Sevki Can; Çırpan, Ali; Soylemez, Saniye (2022-10-01)
An amino-functionalized, conjugated polymer (P(BDBT)) modified glassy carbon electrode (GCE) was employed as an immobilization platform for glucose oxidase (GOx) enzyme to assemble a novel glucose biosensor. Amino groups available on the polymer backbone served as bioconjugation sites for GOx via glutaraldehyde (GA). The biosensor response to the reduction in oxygen amount because of the enzyme reaction was monitored at –0.7 V potential versus Ag/AgCl. The biosensor displayed a broad linear range between 0....
A newly designed anthracene and isoindigo based polymer: synthesis, electrochemical characterization and biosensor applications
Soylemez, Saniye; Goker, Seza; Toppare, Levent Kamil (Royal Society of Chemistry (RSC), 2019-09-21)
A glucose biosensor based on a newly designed and synthesized polymer, poly[(E)-6-methyl-6 '-(10-methylanthracen-9-yl)-1,1 '-diundecyl-[3,3 '-biindolinylidene]-2,2 '-dione] (namely PIIDAnth), and single walled carbon nanotubes (SWCNTs) was fabricated via an easy one pot electrode preparation and explored as a glucose electrochemical sensor. The key aim of this paper is to emphasize creation of the new surface design of sensing platforms based on a novel polymer and nanomaterial for glucose detection. With t...
A benzimidazole-based conducting polymer and a PMMA-clay nanocomposite containing biosensor platform for glucose sensing
EMRE, FATMA BİLGE; Kesik, Melis; Kanik, Fulya Ekiz; Akpinar, Hava Zekiye; Aslan-Gurel, Evren; Rossi, Rene M.; Toppare, Levent Kamil (2015-09-01)
Development of materials composed of polymer-clay nanocomposites (PCN) and conducting polymers attracts great interest and preferred in various applications. Hereby, polymethylmethacrylate (PMMA) layered silicate nanocomposites were prepared by in-situ suspension polymerization by grafting PMMA with laponite using a suitable grafting agent. The properties of the as-synthesized PCN materials are characterized by differential scanning calorimetry (DSC), thermal gravimetry analysis (TGA) and gel permeation chr...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
U. BULUT et al., “A flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensing,”
Microchemical Journal
, vol. 184, pp. 0–0, 2023, Accessed: 00, 2023. [Online]. Available: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85142124632&origin=inward.