Surface Characterization and Biocompatibility of Selenium-Doped Hydroxyapatite Coating on Titanium Alloy

Date

2016-11-01

Author

Yilmaz, Bengi
Evis, Zafer
Tezcaner, Ayşen
Banerjee, Sreeparna

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Selenium-doped hydroxyapatite (HA) was biomimetically coated on Ti6Al4V plates with the aim of combining the anticancer and antibacterial properties of selenium with the biocompatibility and bioactivity of HA. For the coating process, the composition of 1.5 x SBF (solution with ion concentrations at 1.5 times that of simulated body fluid, SBF) was modified to include 0.15 mM selenate (SeO42-) ion. The selenium-doped HA coating was characterized by several methods, such as scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy. The cytotoxicity of selenium on osteoblast and osteosarcoma cells was determined. The coating was shown to inhibit the growth of Staphylococcus epidermidis.

Subject Keywords

Hydroxyapatite, Selenium, Selenium compounds, Coatings, Dopants, Doping

URI

https://hdl.handle.net/11511/34465

Journal

INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY

DOI

https://doi.org/10.1111/ijac.12577

Collections

Department of Engineering Sciences, Article

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Citation Formats

B. Yilmaz, Z. Evis, A. Tezcaner, and S. Banerjee, “Surface Characterization and Biocompatibility of Selenium-Doped Hydroxyapatite Coating on Titanium Alloy,” INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY, pp. 1059–1068, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/34465.