Rigid, Complete Annuloplasty Rings Increase Anterior Mitral Leaflet Strains in the Normal Beating Ovine Heart

Bothe, Wolfgang
Kuhl, Ellen
Kvitting, JPE
Rausch, Manuel
Göktepe, Serdar
Swanson, Julia
Farahmandnia, Saideh
Ingels, Neil
Miller, Craig
Background-Annuloplasty ring or band implantation during surgical mitral valve repair perturbs mitral annular dimensions, dynamics, and shape, which have been associated with changes in anterior mitral leaflet (AML) strain patterns and suboptimal long-term repair durability. We hypothesized that rigid rings with nonphysiological three-dimensional shapes, but not saddle-shaped rigid rings or flexible bands, increase AML strains.


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Vibration analysis seldom has been used in detecting structural and mechanical changes in physiologic and pathologic bone conditions. We sought to correlate natural frequency of the radius measured by vibration analyses with bone mineral density measured by dual-energy xray absorptiometry and quantitative computed tomography (including cortical thickness). Sixty sedentary men between 50 and 70 years old were deemed osteopenic or healthy. A higher natural frequency of the dominant and nondominant radius was ...
Anterior mitral leaflet curvature in the beating ovine heart: a case study using videofluoroscopic markers and subdivision surfaces
Göktepe, Serdar; Kvitting, JPE; Swanson, Julia; Ingels, Neil; Miller, Craig; Kuhl, Ellen (Springer Science and Business Media LLC, 2010-06-01)
The implantation of annuloplasty rings is a common surgical treatment targeted to re-establish mitral valve competence in patients with mitral regurgitation. It is hypothesized that annuloplasty ring implantation influences leaflet curvature, which in turn may considerably impair repair durability. This research is driven by the vision to design repair devices that optimize leaflet curvature to reduce valvular stress. In pursuit of this goal, the objective of this manuscript is to quantify leaflet curvature...
Vibration measurements predict the mechanical properties of human tibia
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Background: Vibration analysis is a promising technique in diagnosing metabolic bone diseases such as osteoporosis and monitoring fracture healing. The aim of this study is to observe the structural dynamic property changes of the tibia extracted from the vibration analysis data.
Citation Formats
W. Bothe et al., “Rigid, Complete Annuloplasty Rings Increase Anterior Mitral Leaflet Strains in the Normal Beating Ovine Heart,” CIRCULATION, pp. 0–0, 2011, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/34545.