Show/Hide Menu
Hide/Show Apps
anonymousUser
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Videos
Videos
Thesis submission
Thesis submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Contact us
Contact us
A biosensor platform based on amine functionalized conjugated benzenediamine-benzodithiophene polymer for testosterone analysis
Download
10.1002:app.49332.pdf
Date
2020-11-01
Author
BULUT, Umut
ŞANLI, SERDAR
Cevher, Sevki Can
Çırpan, Ali
Donmez, Sude
TİMUR, SUNA
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
128
views
29
downloads
Cite This
A novel benzenediamine‐benzodithiophene polymer is synthesized for use in biosensor fabrication for the detection of testosterone. The sensory platform is constructed via drop coating on a screen‐printed carbon electrode, using poly(benzenediamine‐Bis[(2‐ethylhexyl)oxy]benzodithiophene) (pBDBT) as the polymer layer. Testosterone antibodies are immobilized on the polymer‐coated electrode surface via glutaraldehyde, which binds to the surface through the amino functional groups on the polymer backbone. The changes in the surface features due to testosterone binding are investigated via electrochemical techniques such as differential pulse voltammetry, cyclic voltammetry, and electrochemical impedance spectrometry as well as contact angle measurements. Surface morphology of the modified electrodes is characterized by atomic force microscopy. The linear range and limit of detection of the sensor are calculated. Impact of possible interfering compounds is investigated. Furthermore, the sensory platform is utilized for testosterone analysis in synthetic biological fluids.
Subject Keywords
Materials Chemistry
,
General Chemistry
,
Surfaces, Coatings and Films
,
Polymers and Plastics
,
Applications
,
Electrochemistry
,
Sensors and actuators
URI
https://hdl.handle.net/11511/36104
Journal
Journal of Applied Polymer Science
DOI
https://doi.org/10.1002/app.49332
Collections
Department of Chemistry, Article
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
U. BULUT, S. ŞANLI, S. C. Cevher, A. Çırpan, S. Donmez, and S. TİMUR, “A biosensor platform based on amine functionalized conjugated benzenediamine-benzodithiophene polymer for testosterone analysis,”
Journal of Applied Polymer Science
, vol. 137, no. 43, pp. 0–0, 2020, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/36104.