Enantioselective direct aldol reactions promoted by phosphine oxide aziridinyl phosphonate organocatalysts

2015-12-15
Doğan, Özdemir
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A series of phosphine oxide based chiral Lewis bases were screened as organocatalysts for silicon tetrachloride mediated direct asymmetric aldol reactions between cyclohexanone and various aromatic aldehydes. One of the phosphine oxide-aziridinyl phosphonate POAP-A Lewis bases formed the aldol products in up to 75% yield and with 65% ee.
Lewis-Base Catalyst, Asymmetric Allylation, Highly Efficient, Aldehydes, Epoxides, Additions, Silicon, Ligand, Binapo
https://hdl.handle.net/11511/36492
TETRAHEDRON-ASYMMETRY
Department of Chemistry, Article

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Citation Formats
Ö. Doğan, “Enantioselective direct aldol reactions promoted by phosphine oxide aziridinyl phosphonate organocatalysts,” TETRAHEDRON-ASYMMETRY, pp. 1348–1353, 2015, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/36492.
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